{"id":"W2014448626","doi":"10.1016/j.cell.2012.01.033","title":"Mutually Exclusive Binding of Telomerase RNA and DNA by Ku Alters Telomerase Recruitment Model","year":2012,"lang":"en","type":"article","venue":"Cell","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":98,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Biology; Telomerase; Telomerase RNA component; Telomerase reverse transcriptase; DNA; RNA; Telomere; Genetics; Cell biology; Computational biology; Molecular biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003363124,0.0004015538,0.0005411225,0.0004027988,0.0006871055,0.0008080481,0.001103667,0.0005421059,0.003503267],"category_scores_gemma":[0.0006869675,0.0004097805,0.0003377911,0.0001982373,0.0005598075,0.001127034,0.0008954937,0.000701962,0.0006026226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004188757,"about_ca_system_score_gemma":0.0005746207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006326585,"about_ca_topic_score_gemma":0.001062152,"domain_scores_codex":[0.9996436,0.00006600136,0.00001954266,0.0001021179,0.00008349258,0.00008522756],"domain_scores_gemma":[0.9997336,0.00006205604,0.00004375733,0.00005165037,0.00003381433,0.00007506461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009655419,0.0001768274,0.001566239,0.0001942104,0.00006544779,0.0003224888,0.0001370297,0.005279078,0.9587443,0.02499758,0.0005786639,0.006972558],"study_design_scores_gemma":[0.0001720766,0.0004576014,0.004321463,0.00002274366,0.0001513331,0.0006428877,0.0003371862,0.11299,0.8612069,0.0136932,0.005914214,0.00009034618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.965257,0.002034239,0.02479219,0.000376976,0.0001370944,0.00004241833,0.00009185615,0.000214673,0.007053533],"genre_scores_gemma":[0.9957895,0.0003236446,0.00170064,0.00004982046,0.0000139957,0.00003350246,0.00004359468,0.00001208646,0.002033192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003503267,"threshold_uncertainty_score":0.01171958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0446842236221844,"score_gpt":0.2891682182306588,"score_spread":0.2444839946084744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}