{"id":"W2014463389","doi":"10.1126/science.1204988","title":"Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of AMA1 with a RON2 Peptide","year":2011,"lang":"en","type":"article","venue":"Science","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":206,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Canadian Institutes of Health Research","keywords":"Bacterial adhesin; Pathogen; Host (biology); Biology; Receptor; Apicomplexa; Cell biology; Peptide; Computational biology; Microbiology; Biochemistry; Plasmodium falciparum; Ecology; Gene; Immunology; Virulence; Malaria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001462026,0.0002598941,0.0002290944,0.00009865044,0.0002074603,0.0003258727,0.000271566,0.0002973858,0.001201659],"category_scores_gemma":[0.0001416281,0.0001517473,0.0002222152,0.00008381042,0.0002472621,0.0003905268,0.0001874253,0.0006277069,0.0003450145],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003158191,"about_ca_system_score_gemma":0.0001302999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004852363,"about_ca_topic_score_gemma":0.0006138497,"domain_scores_codex":[0.9999479,0.000009246642,0.000002343558,0.00001044851,0.00001929251,0.00001064935],"domain_scores_gemma":[0.9999347,0.00001078009,0.00002025574,0.000005213379,0.000007448523,0.00002162291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002107632,0.00004491938,0.001128912,0.00008279007,0.00002902377,0.0006093143,0.00007611218,0.001089861,0.9940317,0.0004775801,0.0001573569,0.002061635],"study_design_scores_gemma":[0.00008722686,0.0004589227,0.0252968,0.00002911326,0.0001006242,0.002552958,0.0002664071,0.02883314,0.9292411,0.0005349611,0.01255547,0.00004326679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951853,0.001803922,0.001652256,0.0002044499,0.00001740013,0.000005241225,0.00005382719,0.00002726586,0.001050241],"genre_scores_gemma":[0.9949956,0.0007766784,0.002736675,0.00007949911,0.000008894969,0.000005285517,0.0002043061,0.00001340563,0.001179567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001201659,"threshold_uncertainty_score":0.004019976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02136211053970145,"score_gpt":0.2429932347548232,"score_spread":0.2216311242151218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}