{"id":"W2014464624","doi":"10.1645/ge-1634.1","title":"Single-Chain Variable Fragment Antibodies Selected by Phage Display Against the Sporozoite Surface Antigen P23 of Cryptosporidium parvum","year":2009,"lang":"en","type":"article","venue":"Journal of Parasitology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Ministry of Environment; Trent University; University of Guelph","keywords":"Cryptosporidium parvum; Biology; Phage display; Panning (audio); Recombinant DNA; Phagemid; Microbiology; Antigen; Single-chain variable fragment; Escherichia coli; Virology; Giardia lamblia; Monoclonal antibody; Antibody; Molecular biology; Bacteriophage; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002106504,0.0004562261,0.00045939,0.0002844786,0.0002235122,0.0004066851,0.0002716903,0.0003310513,0.001739794],"category_scores_gemma":[0.0002202512,0.0002300667,0.000213324,0.0003385898,0.0001624564,0.0001368725,0.0002590923,0.0005363094,0.0005789232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003555327,"about_ca_system_score_gemma":0.0001505416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004867681,"about_ca_topic_score_gemma":0.0008041882,"domain_scores_codex":[0.9997601,0.00003629554,0.00001229931,0.00005256054,0.00007248859,0.00006629243],"domain_scores_gemma":[0.9998606,0.00004139173,0.00002027894,0.00001442068,0.00002776035,0.0000355267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000643294,0.00003319513,0.0003093804,0.00001568222,0.00000456966,0.00003960718,0.00001303987,0.00004380856,0.9977522,0.00004504166,0.00004588029,0.001633315],"study_design_scores_gemma":[0.00004203333,0.0005506239,0.007843278,0.000006810368,0.00004177255,0.0006576494,0.00002955627,0.002786134,0.9847367,0.00005713792,0.003238249,0.00001007663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914021,0.0003165631,0.006303378,0.00004688319,0.00001675948,0.00009419332,0.0002335932,0.0000900441,0.001496434],"genre_scores_gemma":[0.9848086,0.0004298368,0.009101363,0.00009078902,0.00001411633,0.00008848373,0.001404211,0.00004836838,0.004014307],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001739794,"threshold_uncertainty_score":0.005820215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01469374062744237,"score_gpt":0.3097874638143205,"score_spread":0.2950937231868782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}