{"id":"W2014464624","doi":"10.1645/ge-1634.1","title":"Single-Chain Variable Fragment Antibodies Selected by Phage Display Against the Sporozoite Surface Antigen P23 of Cryptosporidium parvum","year":2009,"lang":"en","type":"article","venue":"Journal of Parasitology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Ministry of Environment; Trent University; University of Guelph","keywords":"Cryptosporidium parvum; Biology; Phage display; Panning (audio); Recombinant DNA; Phagemid; Microbiology; Antigen; Single-chain variable fragment; Escherichia coli; Virology; Giardia lamblia; Monoclonal antibody; Antibody; Molecular biology; Bacteriophage; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000730079,0.0002528453,0.0008701532,0.0001312017,0.0001508634,0.00001987778,0.0003283105,0.0001710719,0.0001232961],"category_scores_gemma":[0.000183894,0.0001543957,0.0002074937,0.0004343773,0.0002686502,0.0001042886,0.00004392701,0.0006242565,0.0000138918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006417929,"about_ca_system_score_gemma":0.0002505392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006147283,"about_ca_topic_score_gemma":0.000007126675,"domain_scores_codex":[0.9974902,0.0002121074,0.0008878225,0.0002136314,0.0006429688,0.0005532764],"domain_scores_gemma":[0.9979721,0.0003328222,0.0006234397,0.0002572674,0.0005922902,0.0002220356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002063115,0.0009349463,0.2187216,0.00007770207,0.0004356039,0.0005233302,0.0003708242,0.0001549565,0.7497224,0.0005903246,0.0245617,0.001843511],"study_design_scores_gemma":[0.003759304,0.006348292,0.6338006,0.0003978152,0.0003024082,0.002256585,0.0003895457,0.0006319344,0.2775186,0.0008451213,0.07330699,0.0004427753],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860664,0.00413152,0.0007625389,0.006865989,0.0003486627,0.000233909,0.00003130708,0.00001273567,0.001546954],"genre_scores_gemma":[0.9945164,0.001591344,0.001881683,0.0007147125,0.0003594855,7.482974e-7,0.00003208804,0.00001716362,0.0008863992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4722037,"threshold_uncertainty_score":0.6296074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01469374062744237,"score_gpt":0.3097874638143205,"score_spread":0.2950937231868782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}