{"id":"W2014489208","doi":"10.1002/cjs.11140","title":"Interim analysis of clinical trials based on urn models","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Statistics","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Interim; Interim analysis; Estimator; Statistics; Computer science; Statistical hypothesis testing; Gaussian; Econometrics; Clinical trial; Mathematics; Medicine; Law","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1141941,0.001384726,0.004684848,0.001895834,0.0007113096,0.00216611,0.00283547,0.001946623,0.003926302],"category_scores_gemma":[0.182282,0.001036598,0.003228104,0.001421049,0.002680199,0.00373464,0.003173686,0.003658835,0.0005809474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001808437,"about_ca_system_score_gemma":0.002925385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000936717,"about_ca_topic_score_gemma":0.0009854467,"domain_scores_codex":[0.888222,0.09897182,0.001902851,0.003203792,0.006228466,0.001471098],"domain_scores_gemma":[0.8507614,0.1218462,0.01011296,0.01025569,0.005580993,0.001442823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.003057425,0.0004379914,0.01120368,0.0009784776,0.001314408,0.0008120402,0.0007943815,0.4115933,0.001893319,0.4217897,0.004272199,0.141853],"study_design_scores_gemma":[0.0002102969,0.0008417538,0.0009126043,0.0001164734,0.0002020537,0.0001104395,0.00004734589,0.8118324,0.001109556,0.1824999,0.002070193,0.0000470081],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.01943561,0.0005123574,0.977361,0.0004757231,0.0001079557,0.0003929278,0.00009107563,0.000229096,0.001394344],"genre_scores_gemma":[0.5468773,0.0006517256,0.4462104,0.000681972,0.0001977224,0.002208516,0.000393607,0.0001828374,0.00259573],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.1141941,"threshold_uncertainty_score":0.6039234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.8794529496569852,"score_gpt":0.6534883635396405,"score_spread":0.2259645861173447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}