{"id":"W2014489208","doi":"10.1002/cjs.11140","title":"Interim analysis of clinical trials based on urn models","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Statistics","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Interim; Interim analysis; Estimator; Statistics; Computer science; Statistical hypothesis testing; Gaussian; Econometrics; Clinical trial; Mathematics; Medicine; Law","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","insufficient_payload"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.05204334,0.0002301631,0.003367621,0.0008832852,0.00005592058,0.00004082265,0.0004748697,0.0002625817,0.002015616],"category_scores_gemma":[0.4694603,0.0001778388,0.0009664534,0.0006432864,0.0003373412,0.0000996944,0.00001635882,0.000673727,0.000009890228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001207027,"about_ca_system_score_gemma":0.001269193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00022946,"about_ca_topic_score_gemma":0.0007784704,"domain_scores_codex":[0.9862888,0.005638197,0.006743234,0.0001836203,0.000665505,0.0004806598],"domain_scores_gemma":[0.8315319,0.1613399,0.0039934,0.0005407662,0.0008734943,0.001720528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0008471442,0.0008405047,0.02715497,0.0001979806,0.005949892,0.0001957244,0.0005396476,0.003511194,0.0000166398,0.7918039,0.08000816,0.08893426],"study_design_scores_gemma":[0.00233828,0.001093214,0.0123018,0.0002504386,0.009447892,0.000008781188,0.0001556358,0.07228445,0.00008885298,0.9000431,0.001603986,0.0003835204],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.005279851,0.0000565145,0.9877902,0.0001784512,0.002168258,0.0001945601,0.002670761,0.000004574003,0.001656829],"genre_scores_gemma":[0.4205098,0.00001050969,0.5786889,0.0002979307,0.0004303498,0.000001422984,0.000004555159,0.00002396588,0.00003253695],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.417417,"threshold_uncertainty_score":0.9988967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.8794529496569852,"score_gpt":0.6534883635396405,"score_spread":0.2259645861173447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}