{"id":"W2014500068","doi":"10.1161/circulationaha.106.655266","title":"Phosphodiesterase Type 5 Is Highly Expressed in the Hypertrophied Human Right Ventricle, and Acute Inhibition of Phosphodiesterase Type 5 Improves Contractility","year":2007,"lang":"en","type":"article","venue":"Circulation","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":528,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; University of Alberta; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"Contractility; Medicine; Sildenafil; Internal medicine; Ventricle; Pulmonary hypertension; Phosphodiesterase 3; cGMP-specific phosphodiesterase type 5; Amrinone; Afterload; Cardiology; Inotrope; Endocrinology; Phosphodiesterase; Protein kinase A; Kinase; Chemistry; Biology; Cell biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01102074681232692,"score_gpt":0.257599014830393,"score_spread":0.2465782680180661,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}