{"id":"W2014514137","doi":"10.1007/s00280-005-0155-8","title":"Antiproliferative and Antiproteolytic activity of Pentoxifylline in cultures of B16F10 Melanoma cells","year":2005,"lang":"en","type":"article","venue":"Cancer Chemotherapy and Pharmacology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Pentoxifylline; Chemistry; Matrix metalloproteinase; Pharmacology; Zymography; Extracellular matrix; MTT assay; Cell adhesion; Cell growth; In vitro; Cytotoxicity; Cell culture; Molecular biology; Cell; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001715182,0.0003503838,0.0003581938,0.0002248145,0.0001613194,0.0002207111,0.0001695463,0.000210375,0.001046089],"category_scores_gemma":[0.0001232847,0.0001324533,0.0002341037,0.0002569057,0.0001589095,0.0001957572,0.0001071947,0.0005427224,0.0002688622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002221508,"about_ca_system_score_gemma":0.0002408694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002403433,"about_ca_topic_score_gemma":0.002780665,"domain_scores_codex":[0.9998424,0.00003254046,0.00001917664,0.00002118883,0.00003422148,0.00005045202],"domain_scores_gemma":[0.9998564,0.00004700792,0.0000209403,0.00002477406,0.00001932905,0.00003161244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002773649,0.00003488438,0.0001187479,0.00002865707,0.000003902954,0.00006223637,0.00001997429,0.00004530051,0.9984652,0.0000311645,0.00003784639,0.0008747809],"study_design_scores_gemma":[0.00001492188,0.0004759475,0.002997166,0.000003718975,0.000008768156,0.0001276658,0.00002316168,0.000220754,0.9952738,0.000009330307,0.0008430103,0.000001770506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921179,0.003518744,0.001065804,0.0001097884,0.00005575752,0.0000308199,0.0007028636,0.00003933926,0.002358981],"genre_scores_gemma":[0.9911986,0.002417629,0.001585083,0.00005637432,0.00002822615,0.00003914973,0.00126772,0.00001648019,0.00339064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002403433,"threshold_uncertainty_score":0.004778922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008637095251625556,"score_gpt":0.2991862646148014,"score_spread":0.2905491693631759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}