{"id":"W2014522656","doi":"10.1097/brs.0b013e31823b055f","title":"Structured Bilaminar Coculture Outperforms Stem Cells and Disc Cells in a Simulated Degenerate Disc Environment","year":2011,"lang":"en","type":"article","venue":"Spine","topic":"Spine and Intervertebral Disc Pathology","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Object Research Systems (Canada); Discovery Air (Canada)","funders":"National Institute of Dental and Craniofacial Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; U.S. Public Health Service; National Institutes of Health","keywords":"Mesenchymal stem cell; Stem cell; Intervertebral disc; Medicine; Cell biology; Bioreactor; Tissue engineering; Regenerative medicine; Regeneration (biology); Embryonic stem cell; Biomedical engineering; Pathology; Anatomy; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002941425,0.0005119487,0.00044343,0.0003352152,0.0002561883,0.0006342328,0.0004844901,0.0005692011,0.001292356],"category_scores_gemma":[0.0003383344,0.0001677425,0.0002759302,0.000243854,0.0004055585,0.000284256,0.0004696787,0.000295533,0.0003514106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005115691,"about_ca_system_score_gemma":0.0003905864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001093411,"about_ca_topic_score_gemma":0.00147112,"domain_scores_codex":[0.999584,0.00004263199,0.00003519238,0.0001061585,0.0001723319,0.00005976671],"domain_scores_gemma":[0.9996803,0.00008259203,0.0000983596,0.00002901798,0.00006086308,0.00004895787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000607357,0.0002713833,0.001239139,0.0002991857,0.00002055163,0.0003568711,0.00008283989,0.002820306,0.9885134,0.0001318461,0.00005585531,0.005601348],"study_design_scores_gemma":[0.00006530921,0.002084095,0.003601758,0.00002278658,0.00006281312,0.0004008809,0.0001307304,0.007537367,0.9842786,0.00005944844,0.001739118,0.00001711103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935503,0.0006772067,0.004474409,0.00003002856,0.000024206,0.00008152021,0.00008349792,0.0000472498,0.001031628],"genre_scores_gemma":[0.9919708,0.0004470648,0.006517518,0.00003909051,0.00000874461,0.0001026836,0.0001421335,0.00001870075,0.0007532518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001292356,"threshold_uncertainty_score":0.004323363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02308435950311796,"score_gpt":0.2312178738865401,"score_spread":0.2081335143834221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}