{"id":"W2014530882","doi":"10.1007/s00335-004-2428-7","title":"Identification and characterization of a new Down syndrome model, Ts[Rb(12.1716)]2Cje, resulting from a spontaneous Robertsonian fusion between T(1716)65Dn and mouseChromosome 12","year":2005,"lang":"en","type":"article","venue":"Mammalian Genome","topic":"Down syndrome and intellectual disability research","field":"Medicine","cited_by":100,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Aging; National Institutes of Health; Down Syndrome Research Foundation; Down Syndrome Research and Treatment Foundation; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Larry L. Hillblom Foundation","keywords":"Biology; Trisomy; Chromosome 21; Robertsonian translocation; Aneuploidy; Population; Genetics; Chromosomal translocation; Chromosomal rearrangement; Chromosome; Karyotype; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002775476,0.0006675527,0.0003792245,0.0008521248,0.0004470375,0.0006075273,0.0004959265,0.0006115725,0.002232232],"category_scores_gemma":[0.0003620856,0.000390193,0.0003918914,0.0002231669,0.0005164716,0.000360101,0.0005570026,0.001008739,0.0008445559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005145408,"about_ca_system_score_gemma":0.0003334768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00114575,"about_ca_topic_score_gemma":0.001484751,"domain_scores_codex":[0.9997873,0.00003289366,0.00003286018,0.00004609438,0.00005495356,0.00004596194],"domain_scores_gemma":[0.999698,0.00009071502,0.00006552953,0.00004425551,0.00002349949,0.00007801917],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006087391,0.00003364522,0.0001137186,0.00001155293,0.000005541297,0.0001759778,0.00001558188,0.00007213839,0.9986745,0.0003647386,0.00004898101,0.0004227054],"study_design_scores_gemma":[0.00007929235,0.0002648628,0.003321827,0.000008917626,0.00007026797,0.002710705,0.00005269562,0.001977998,0.9817744,0.000151813,0.009564572,0.0000225675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981595,0.0007402253,0.01324605,0.0002254532,0.00009658514,0.0001134982,0.00133721,0.0001815606,0.002464506],"genre_scores_gemma":[0.9758155,0.000891155,0.01007593,0.00009245576,0.00001959587,0.00008713474,0.004653781,0.0001426146,0.008221779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002232232,"threshold_uncertainty_score":0.007467508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03105234712952648,"score_gpt":0.2708158704187178,"score_spread":0.2397635232891913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}