{"id":"W2014628254","doi":"10.1289/ehp.8247","title":"Meeting Report: Validation of Toxicogenomics-Based Test Systems: ECVAM–ICCVAM/NICEATM Considerations for Regulatory Use","year":2005,"lang":"en","type":"article","venue":"Environmental Health Perspectives","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"","keywords":"Toxicogenomics; Test (biology); Computer science; Engineering; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0908725,0.001725703,0.00136773,0.002616603,0.003313248,0.007702842,0.01033516,0.02235577,0.01188552],"category_scores_gemma":[0.04859616,0.001061461,0.003461372,0.001246494,0.001916215,0.004313621,0.004908202,0.009631682,0.01092957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005007613,"about_ca_system_score_gemma":0.01925544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01023653,"about_ca_topic_score_gemma":0.009316049,"domain_scores_codex":[0.94138,0.01676708,0.004714764,0.002789401,0.03090785,0.003440895],"domain_scores_gemma":[0.9392315,0.01156872,0.00405328,0.004478874,0.03797574,0.002691877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00121752,0.0009396159,0.004777569,0.003740148,0.0002711671,0.003474321,0.002159965,0.006363234,0.06998196,0.02951422,0.7339211,0.1436392],"study_design_scores_gemma":[0.0001108702,0.0007260632,0.005685863,0.001185116,0.0001036945,0.001015962,0.0006042646,0.001673591,0.02266457,0.003975908,0.9620615,0.0001926163],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.04984825,0.03561266,0.178973,0.2955849,0.03187023,0.0183157,0.01484546,0.004995344,0.3699545],"genre_scores_gemma":[0.1720339,0.01530672,0.2695415,0.1115388,0.006960197,0.01529544,0.02896972,0.003005156,0.3773487],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.0908725,"threshold_uncertainty_score":0.4805855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04175550240964866,"score_gpt":0.3220159537253427,"score_spread":0.280260451315694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}