{"id":"W2014645588","doi":"10.1016/j.nbd.2006.01.016","title":"Transgenic expression of human FGF-1 protects against hypoxic–ischemic injury in perinatal brain by intervening at caspase-XIAP signaling cascades","year":2006,"lang":"en","type":"article","venue":"Neurobiology of Disease","topic":"Neonatal and fetal brain pathology","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institutes of Health; Brock University; National Institute of Neurological Disorders and Stroke; American Heart Association","keywords":"XIAP; Neuroprotection; TUNEL assay; Inhibitor of apoptosis; Apoptosis; Caspase 3; Ischemia; Biology; Brain damage; Caspase; Hypoxia (environmental); Hippocampal formation; Cell biology; Pathology; Programmed cell death; Neuroscience; Medicine; Internal medicine; Chemistry; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001407024,0.0002219147,0.0004775898,0.0001760939,0.00005571956,0.000001998621,0.0001499009,0.0001654743,0.00005897032],"category_scores_gemma":[0.0001109413,0.0001996402,0.0002014611,0.0001363746,0.0003988204,0.0000582749,0.0001108887,0.00029572,0.000003491137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003480939,"about_ca_system_score_gemma":0.0000431568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004070537,"about_ca_topic_score_gemma":0.000007052159,"domain_scores_codex":[0.9984437,0.0001762304,0.0005348736,0.0004297385,0.0001061868,0.0003092993],"domain_scores_gemma":[0.9992929,0.0001015285,0.0001943555,0.0002408025,0.00003738549,0.0001330192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001261328,0.0002724162,0.008463117,0.0005163415,0.000009612002,0.00007095971,0.0001140956,0.00001103889,0.988437,0.000007430975,0.0004230569,0.0004136139],"study_design_scores_gemma":[0.0017069,0.0009147543,0.01397627,0.0003144642,0.0000260726,0.0000177011,0.00002746392,0.000007802763,0.9826261,0.00005078173,0.0001755692,0.0001561459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982442,0.0005544925,0.00001465892,0.0002522403,0.00004964429,0.0004779248,0.0002149844,0.00003699315,0.0001548633],"genre_scores_gemma":[0.9990159,0.000005652427,0.00007675235,0.0002704624,0.00004162581,0.00004586167,0.000252339,0.00002891051,0.0002625016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00581091,"threshold_uncertainty_score":0.8141091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009617025386876633,"score_gpt":0.2552913486009236,"score_spread":0.245674323214047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}