{"id":"W2014672110","doi":"10.1016/s0014-5793(00)02320-6","title":"C3A binds to the seven transmembrane anaphylatoxin receptor expressed by epithelial cells and triggers the production of IL‐8","year":2001,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Anaphylatoxin; Flow cytometry; Pertussis toxin; Downregulation and upregulation; Receptor; Complement system; Cell biology; Molecular biology; Chemistry; Biology; Immunology; Immune system; Biochemistry; G protein; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001297792,0.0003514394,0.0002293337,0.0002922782,0.0003143735,0.0003357382,0.0001682873,0.0005574928,0.002166089],"category_scores_gemma":[0.0001213758,0.0001174306,0.0003097736,0.000234832,0.0002259384,0.0001764399,0.00023793,0.0006165674,0.0009351528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004598266,"about_ca_system_score_gemma":0.0002171275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001129229,"about_ca_topic_score_gemma":0.0007773594,"domain_scores_codex":[0.9997502,0.00004390043,0.00001171566,0.00002969519,0.00006096028,0.0001035912],"domain_scores_gemma":[0.999926,0.00001575581,0.0000144579,0.00001043146,0.00001818142,0.000015184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005655746,0.00001191217,0.0001303153,0.00002522596,0.000003369895,0.00008600583,0.000007470545,0.00001769905,0.9988068,0.00007526227,0.00006293696,0.0007164741],"study_design_scores_gemma":[0.00001379765,0.0002009871,0.007624515,0.00001380198,0.00001009396,0.0005122591,0.00005797472,0.0006502056,0.9878175,0.0001210165,0.002972281,0.000005637763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830362,0.004791684,0.006389208,0.0005028872,0.00009801266,0.00006850273,0.0005595815,0.0001124826,0.004441347],"genre_scores_gemma":[0.9927803,0.00186044,0.00204456,0.0001415473,0.00002498782,0.0000370471,0.0005004453,0.000009498951,0.002601333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002166089,"threshold_uncertainty_score":0.007246315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009323021730069833,"score_gpt":0.2137426428519069,"score_spread":0.2044196211218371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}