{"id":"W2014680768","doi":"10.1139/y02-123","title":"Antisense inhibition of Flk-1 by oligonucleotides composed of 2<i>'</i>-deoxy-2<i>'</i>-fluoro-β-<scp>D</scp>-arabino- and 2<i>'</i>-deoxy-nucleosides","year":2002,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Health Canada; Heart and Stroke Foundation of Canada","keywords":"Oligonucleotide; RNA; RNase P; Antisense RNA; DNA; Molecular biology; RNase H; Chemistry; Biochemistry; Sense (electronics); Biology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001514017,0.0005029792,0.0003304856,0.0001022493,0.00008018773,0.0001854161,0.0001509517,0.0002697632,0.000511352],"category_scores_gemma":[0.0001341663,0.0001477911,0.0002523929,0.00009342223,0.0001992943,0.0001682438,0.00009863529,0.000363379,0.0001125829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002543324,"about_ca_system_score_gemma":0.0001949114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004977552,"about_ca_topic_score_gemma":0.0007655931,"domain_scores_codex":[0.999868,0.00002097824,0.00001207184,0.00004743318,0.00002313623,0.00002834634],"domain_scores_gemma":[0.999917,0.00002398542,0.00003053806,0.00000518155,0.000007580984,0.00001570211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005565715,0.00001016521,0.00004196945,0.00002243744,0.000004318242,0.000008331634,0.000006544616,0.00005838657,0.9994174,0.00002221223,0.000005655451,0.0003469059],"study_design_scores_gemma":[0.00001395548,0.0004877977,0.0005703925,0.000002820343,0.0000208448,0.0000544392,0.000006715074,0.0003278179,0.9980432,0.000007337569,0.0004616786,0.000003006075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953851,0.001627794,0.002160989,0.00003167364,0.00002646058,0.00002475026,0.0001114831,0.00004322656,0.0005885967],"genre_scores_gemma":[0.9945575,0.001033829,0.00315265,0.00004589434,0.00001533745,0.0000492219,0.0002472722,0.00001260498,0.000885748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000511352,"threshold_uncertainty_score":0.0018453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006786813671682481,"score_gpt":0.2097486845379604,"score_spread":0.2029618708662779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}