{"id":"W2014736805","doi":"10.1126/stke.4082007pe56","title":"Receptors Look Outward: Revealing Signals That Bring Excitation to Synapses","year":2007,"lang":"en","type":"review","venue":"Science s STKE","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Neuroscience; Synapse; Silent synapse; Glutamate receptor; Scaffold protein; Biology; Receptor; Excitatory postsynaptic potential; Cell biology; Signal transducing adaptor protein; Chemistry; AMPA receptor; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004203485,0.0006348938,0.001181836,0.002425746,0.001082486,0.0006261097,0.003626996,0.0002140079,0.0001906711],"category_scores_gemma":[0.005002832,0.0005323163,0.0003461051,0.007393107,0.002095973,0.001097155,0.001023944,0.001107962,0.001893249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003587573,"about_ca_system_score_gemma":0.001396726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000107533,"about_ca_topic_score_gemma":0.000002104831,"domain_scores_codex":[0.9912692,0.0006345867,0.0008223584,0.002678554,0.002575019,0.002020338],"domain_scores_gemma":[0.9959305,0.00179349,0.0004385842,0.0008401868,0.0001689774,0.0008282583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001753021,0.00009379437,0.00001444407,0.001609674,0.000004705954,0.0003432588,0.0002940463,0.0000220557,0.1513687,0.0002143554,0.0009708218,0.8450466],"study_design_scores_gemma":[0.0001193437,0.0002629575,0.000007866874,0.002498346,0.00006529069,0.0001915594,0.00005151987,0.00002304142,0.1028371,0.00007155069,0.893093,0.0007783209],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01925128,0.9517167,0.0006387159,0.0004884176,0.01377984,0.007052571,0.0001080427,0.0008348598,0.006129604],"genre_scores_gemma":[0.002834293,0.9915689,0.0001451989,0.001897258,0.0002930223,0.0001039565,0.000001292565,0.00008534834,0.003070768],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8921223,"threshold_uncertainty_score":0.9997128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3022933600034461,"score_gpt":0.4866091614073717,"score_spread":0.1843158014039256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}