{"id":"W2014755754","doi":"10.1038/sj.cgt.7700655","title":"Kinase-dead PKB gene therapy combined with hyperthermia for human breast cancer","year":2003,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Hospital; Women's College Hospital; Sunnybrook Health Science Centre; Princess Margaret Cancer Centre; University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Cancer research; Protein kinase B; Clonogenic assay; Apoptosis; Kinase; Breast cancer; Cancer cell; Biology; Cancer; Hyperthermia; Chemistry; Medicine; Cell biology; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002108227,0.0003145033,0.0004585093,0.0003747874,0.0002393779,0.0002611512,0.0002792756,0.0003552697,0.001366003],"category_scores_gemma":[0.000158883,0.0002446269,0.0003209919,0.0002498178,0.0003778966,0.0003855711,0.0002833507,0.0005727411,0.000247182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000437244,"about_ca_system_score_gemma":0.0003075407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00106344,"about_ca_topic_score_gemma":0.0009821123,"domain_scores_codex":[0.9998698,0.00002436161,0.000006333869,0.00002506575,0.00003437983,0.00004011047],"domain_scores_gemma":[0.9999666,0.00001013225,0.000006076882,0.000007962318,0.000002631861,0.000006549149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007660125,0.000103928,0.0001534536,0.0001595948,0.0000251377,0.0001166919,0.00007815838,0.001091107,0.9852663,0.001120381,0.0003037767,0.01081545],"study_design_scores_gemma":[0.0001545186,0.0006580665,0.000883757,0.000007613849,0.00005086626,0.0004661676,0.0000172391,0.001253638,0.9918205,0.0002031593,0.004476711,0.000007822853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9722269,0.01112433,0.01028869,0.0005567354,0.0002635045,0.0001395743,0.0003104741,0.0002758719,0.004813794],"genre_scores_gemma":[0.9926156,0.002401912,0.002468457,0.00003869724,0.00002448386,0.00004669439,0.00009576426,0.00003106855,0.002277414],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001366003,"threshold_uncertainty_score":0.004569709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0297118240860409,"score_gpt":0.3210344027562675,"score_spread":0.2913225786702266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}