{"id":"W2014764509","doi":"10.1002/1098-2795(200008)56:4<458::aid-mrd3>3.0.co;2-l","title":"Genetic reprogramming of lactate dehydrogenase, citrate synthase, and phosphofructokinase mRNA in bovine nuclear transfer embryos produced using bovine fibroblast cell nuclei","year":2000,"lang":"en","type":"article","venue":"Molecular Reproduction and Development","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Institute of Environmental Health Sciences","keywords":"Biology; Blastocyst; Embryo; Phosphofructokinase; Somatic cell nuclear transfer; Molecular biology; Cytoplast; Reprogramming; Oocyte; Andrology; Cell culture; Cell; Embryogenesis; Biochemistry; Glycolysis; Genetics; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005485554,0.0002805985,0.0004498362,0.0001583443,0.0001240339,0.00001903822,0.00005760393,0.0001252615,0.0001456422],"category_scores_gemma":[0.0000775812,0.0002640799,0.00005561288,0.0003229395,0.0002309012,0.00008878329,0.00003883199,0.0002184976,0.000006886821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006717794,"about_ca_system_score_gemma":0.0001204232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007556434,"about_ca_topic_score_gemma":0.000004129591,"domain_scores_codex":[0.9974501,0.0001095411,0.0006314372,0.001275096,0.0002023749,0.0003314695],"domain_scores_gemma":[0.9990265,0.000008222391,0.00007992597,0.0006165658,0.0001136689,0.0001551182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004810915,0.0005089568,0.01115403,0.000383545,0.00008833594,0.000148811,0.001149175,0.00006282705,0.9256703,0.000004887937,0.00001262704,0.05600561],"study_design_scores_gemma":[0.00164558,0.0004103951,0.1482163,0.0001580926,0.00006300865,0.0003889586,0.0001374386,0.000149791,0.8444765,0.00002545247,0.00401238,0.0003160814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963042,0.002194277,0.0001187202,0.0002455169,0.00005708934,0.0008304313,0.000002789822,0.00005642763,0.0001906062],"genre_scores_gemma":[0.990153,0.0001819885,0.009249,0.00008773987,0.00004295041,0.00001833428,0.00001449549,0.00004008546,0.0002123678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1370622,"threshold_uncertainty_score":0.9999812,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01274831846958181,"score_gpt":0.2291025263534383,"score_spread":0.2163542078838565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}