{"id":"W2014764509","doi":"10.1002/1098-2795(200008)56:4<458::aid-mrd3>3.0.co;2-l","title":"Genetic reprogramming of lactate dehydrogenase, citrate synthase, and phosphofructokinase mRNA in bovine nuclear transfer embryos produced using bovine fibroblast cell nuclei","year":2000,"lang":"en","type":"article","venue":"Molecular Reproduction and Development","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Institute of Environmental Health Sciences","keywords":"Biology; Blastocyst; Embryo; Phosphofructokinase; Somatic cell nuclear transfer; Molecular biology; Cytoplast; Reprogramming; Oocyte; Andrology; Cell culture; Cell; Embryogenesis; Biochemistry; Glycolysis; Genetics; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001519739,0.0001439321,0.0001479145,0.0001495276,0.0001030894,0.0002382503,0.0001323649,0.000202252,0.0007574672],"category_scores_gemma":[0.0002120392,0.0001352724,0.000171628,0.00008146345,0.0001608419,0.000160055,0.0001374008,0.0002525746,0.0002489634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002718216,"about_ca_system_score_gemma":0.0001817894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001094913,"about_ca_topic_score_gemma":0.001786842,"domain_scores_codex":[0.9998078,0.0000236101,0.00002089831,0.00005950456,0.0000613103,0.00002700025],"domain_scores_gemma":[0.9998719,0.0000351479,0.00003750266,0.00001703773,0.00002014332,0.00001831358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001250707,0.000002507237,0.0001503801,0.000007854548,6.462864e-7,0.00002395318,0.00001817389,0.00001166298,0.9992409,0.00003046323,0.000004065481,0.0004970459],"study_design_scores_gemma":[0.000008614537,0.0001748013,0.01178009,0.00001130597,0.00001604143,0.000353384,0.00007254545,0.0005770099,0.9832772,0.00003622884,0.003687039,0.00000582826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986112,0.001003521,0.009603462,0.00004781991,0.00004140343,0.0000383077,0.0003367676,0.00005087467,0.002765935],"genre_scores_gemma":[0.9855788,0.0008487488,0.005540716,0.00005275009,0.00000993979,0.00005867002,0.000826914,0.00003995941,0.007043489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001094913,"threshold_uncertainty_score":0.002533913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01274831846958181,"score_gpt":0.2291025263534383,"score_spread":0.2163542078838565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}