{"id":"W2014875183","doi":"10.1159/000194041","title":"Alpha <sub>1</sub> -Antitrypsin Deficiency: Genetic, Clinical and Functional Correlations in a Three Generation Family","year":2009,"lang":"en","type":"article","venue":"Respiration","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame","funders":"","keywords":"Medicine; Heterozygote advantage; Elastic recoil; Pulmonary function testing; Respiratory disease; Internal medicine; Lung volumes; Family history; Cystic fibrosis; Disease; Obstructive lung disease; Lung; Gastroenterology; COPD; Endocrinology; Genotype; Genetics; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003416497,0.001014377,0.0004402225,0.0009507317,0.001126585,0.0003656562,0.0003331187,0.0008075847,0.002485119],"category_scores_gemma":[0.001495458,0.0004178667,0.0003705049,0.0007356163,0.0007473903,0.0003215923,0.0003211704,0.0007192591,0.0004201553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000306667,"about_ca_system_score_gemma":0.0002653408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002594516,"about_ca_topic_score_gemma":0.001894502,"domain_scores_codex":[0.9997079,0.0000639381,0.00003232602,0.00008257509,0.00006532339,0.00004800127],"domain_scores_gemma":[0.9992712,0.0002324082,0.0001737849,0.00004459284,0.00006463553,0.0002133153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001331611,0.000866246,0.7633784,0.00008709227,0.0002219288,0.18627,0.00291614,0.0004212486,0.02586912,0.0006012658,0.0009888157,0.01704813],"study_design_scores_gemma":[0.0001007416,0.001159346,0.5906356,0.00003797954,0.0002081453,0.4008377,0.0006993287,0.001027606,0.00292287,0.00052757,0.001788536,0.00005460537],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990006,0.0002287263,0.0002642889,0.00006436378,0.000005897311,0.000008655687,0.00005239449,0.00000880506,0.000366246],"genre_scores_gemma":[0.9989039,0.0002212391,0.0003677929,0.00005370591,0.00002206435,0.000008319073,0.00008304984,0.00000764416,0.0003322932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002594516,"threshold_uncertainty_score":0.008313596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09246478323163493,"score_gpt":0.3340927304111518,"score_spread":0.2416279471795169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}