{"id":"W2014884192","doi":"10.1172/jci45589","title":"Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8–mediated activation of TGF-β","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":195,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Liver Center, University of California, San Francisco; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; Burroughs Wellcome Fund; University of California, San Francisco; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Gladstone Institutes","keywords":"Chemokine; Fibroblast; Immunology; Immune system; Fibrosis; Inflammation; Cell biology; Acquired immune system; Lung; Integrin; Biology; Dendritic cell; Medicine; Cell; Pathology; Cell culture; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002963256,0.0002401691,0.0001352315,0.0001985534,0.0001532086,0.0003786166,0.0001438981,0.0003170798,0.002695699],"category_scores_gemma":[0.000129639,0.0001325269,0.00021079,0.0001002579,0.0002152037,0.0001806341,0.0001467806,0.0004758799,0.0006407984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001753806,"about_ca_system_score_gemma":0.0001611936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000506628,"about_ca_topic_score_gemma":0.0008441496,"domain_scores_codex":[0.9997976,0.0000450096,0.000023493,0.00003579816,0.00005564907,0.00004238539],"domain_scores_gemma":[0.9999406,0.00001200125,0.00001487107,0.00001370664,0.000005819446,0.00001294974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000150978,0.00003843261,0.0002582451,0.00002244923,0.000003277384,0.00006145557,0.00002479811,0.00004140702,0.9973094,0.0003024629,0.00007819792,0.001708915],"study_design_scores_gemma":[0.00007392433,0.0004383484,0.004418836,0.0000155937,0.00002669201,0.001030286,0.00009753714,0.0006614125,0.9824892,0.000202373,0.01053931,0.000006524444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819234,0.006041365,0.006264777,0.000322033,0.00007513704,0.00006761034,0.0006749071,0.00009844868,0.004532338],"genre_scores_gemma":[0.9902332,0.001886478,0.00282354,0.0000851374,0.00001260393,0.00007218341,0.0006350644,0.00001945761,0.004232273],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002695699,"threshold_uncertainty_score":0.009018064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1149602936796589,"score_gpt":0.401495364864295,"score_spread":0.2865350711846361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}