{"id":"W2014884192","doi":"10.1172/jci45589","title":"Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8–mediated activation of TGF-β","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":195,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Liver Center, University of California, San Francisco; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; Burroughs Wellcome Fund; University of California, San Francisco; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Gladstone Institutes","keywords":"Chemokine; Fibroblast; Immunology; Immune system; Fibrosis; Inflammation; Cell biology; Acquired immune system; Lung; Integrin; Biology; Dendritic cell; Medicine; Cell; Pathology; Cell culture; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001906177,0.0001377248,0.0005161244,0.0002125908,0.00007592107,0.00001898306,0.00008781481,0.0002492448,0.00004662264],"category_scores_gemma":[0.003562195,0.0001141942,0.00009088591,0.0002178383,0.0004443586,0.0005938282,0.00003580315,0.0006911314,0.000002487087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005842352,"about_ca_system_score_gemma":0.0003420357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004803453,"about_ca_topic_score_gemma":0.00001301336,"domain_scores_codex":[0.9969012,0.0003462643,0.001842147,0.0001955165,0.0005299657,0.0001849459],"domain_scores_gemma":[0.9966874,0.0008155706,0.001229446,0.0001728119,0.0006889594,0.0004058081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002810742,0.0004781015,0.1986462,0.004790988,0.0002087117,0.00004294542,0.005809519,0.00004071804,0.7552422,0.001504992,0.001240354,0.02918459],"study_design_scores_gemma":[0.004862642,0.003450971,0.3742385,0.001780221,0.0001320139,0.00004091813,0.0002372436,0.001033518,0.6112562,0.001965978,0.0008263927,0.0001754197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982452,0.0002675418,0.0002159552,0.0006929679,0.00006758242,0.0003170302,0.000002663495,0.00001451415,0.0001765083],"genre_scores_gemma":[0.9955789,0.0003047306,0.00357554,0.0001937341,0.0002144419,0.000003433543,0.000009341032,0.0000216817,0.00009816053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1755923,"threshold_uncertainty_score":0.4656705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1149602936796589,"score_gpt":0.401495364864295,"score_spread":0.2865350711846361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}