{"id":"W2014899966","doi":"10.1016/j.yjmcc.2014.10.001","title":"Detailed characterization of microRNA changes in a canine heart failure model: Relationship to arrhythmogenic structural remodeling","year":2014,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; McGill University; Montreal Heart Institute","funders":"Heart and Stroke Foundation of Canada","keywords":"Extracellular matrix; Fibrosis; Heart failure; microRNA; Fibroblast; Cardiac fibrosis; Ventricular remodeling; Internal medicine; Atrial fibrillation; Ejection fraction; Extracellular; Medicine; Gene expression; Cardiology; Biology; Cell biology; Cell culture; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005057025,0.0001229675,0.0006635751,0.0002651314,0.00002878265,0.000007265003,0.00004314379,0.0001478025,0.000001849728],"category_scores_gemma":[0.0001018017,0.0001020487,0.0002234121,0.0001350295,0.00002866718,0.00003631981,0.00003028487,0.000241674,3.895942e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003608756,"about_ca_system_score_gemma":0.00006064062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004186431,"about_ca_topic_score_gemma":0.000008336255,"domain_scores_codex":[0.9989271,0.0001416705,0.0004463362,0.0001541433,0.0001610417,0.0001697365],"domain_scores_gemma":[0.9993262,0.00002306336,0.0001798133,0.0001500493,0.0002028507,0.0001179731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000137811,0.000004272227,0.0202995,0.00004534316,0.00005077306,0.00001474746,0.0001295949,0.03091625,0.9480872,0.0000548739,0.000005947207,0.0002536929],"study_design_scores_gemma":[0.006361785,0.001920683,0.1616991,0.001005121,0.001091183,0.006019185,0.0003154777,0.2171578,0.602038,0.0009322719,0.0007723903,0.0006870452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.938279,0.0006534743,0.05961684,0.001186031,0.00009621096,0.0001403604,0.000003726398,0.000003889118,0.00002049707],"genre_scores_gemma":[0.9946353,0.00003766404,0.004896881,0.0001892798,0.0001956284,0.000001478899,0.00001605397,0.0000190411,0.000008626437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3460492,"threshold_uncertainty_score":0.4161426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01070552888970974,"score_gpt":0.2317255182571143,"score_spread":0.2210199893674045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}