{"id":"W2014907409","doi":"10.1021/bi052054x","title":"Mechanistic Analysis of the Unusual Redox-Elimination Sequence Employed by <i>Thermotoga maritima </i>BglT:  A 6-Phospho-β-glucosidase from Glycoside Hydrolase Family 4","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Kinetic isotope effect; Leaving group; Stereochemistry; Oxocarbenium; Glycosidic bond; Deprotonation; Transition state; Elimination reaction; Concerted reaction; Crystallography; Deuterium; Enzyme; Nucleophile; Medicinal chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001770386,0.0004018283,0.0002008411,0.00007680448,0.0001660052,0.0003670468,0.0003839839,0.0003569807,0.0006822834],"category_scores_gemma":[0.0001004937,0.0001127731,0.0002442857,0.00009336131,0.0002194751,0.0003536031,0.0001942383,0.0005429038,0.000239023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004176405,"about_ca_system_score_gemma":0.0002638222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009698056,"about_ca_topic_score_gemma":0.001263536,"domain_scores_codex":[0.9999387,0.000007503474,0.000003954618,0.0000147253,0.00001739234,0.00001766017],"domain_scores_gemma":[0.9999571,0.000007665952,0.00001455097,0.000005023102,0.000008351921,0.000007348282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002397097,0.00005822835,0.0009350432,0.0001226701,0.00001176114,0.0001670914,0.0000371176,0.001339139,0.9932032,0.0007029386,0.00009176835,0.003091288],"study_design_scores_gemma":[0.00001462848,0.0002971925,0.003971772,0.00000733879,0.00001828322,0.0002094871,0.00007204307,0.00532262,0.9883041,0.0004031972,0.001367246,0.00001209352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921259,0.0006834802,0.003936931,0.0002019997,0.00001658426,0.0000472776,0.0003438379,0.00008239975,0.002561584],"genre_scores_gemma":[0.9972501,0.0005040763,0.001479941,0.00004418321,0.000003448072,0.00001880243,0.0002241977,0.000009950435,0.0004652024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009698056,"threshold_uncertainty_score":0.003030181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01006695155332476,"score_gpt":0.2222938040036097,"score_spread":0.2122268524502849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}