{"id":"W2014909583","doi":"10.1161/01.atv.0000100404.05459.39","title":"Apolipoprotein D Inhibits Platelet-Derived Growth Factor-BB–Induced Vascular Smooth Muscle Cell Proliferated by Preventing Translocation of Phosphorylated Extracellular Signal Regulated Kinase 1/2 to the Nucleus","year":2003,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Adipokines, Inflammation, and Metabolic Diseases","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; University of Ottawa","keywords":"Platelet-derived growth factor receptor; Vascular smooth muscle; Platelet-derived growth factor; Growth factor; Biology; Endocrinology; Cell growth; MAPK/ERK pathway; Internal medicine; Fibroblast growth factor; Signal transduction; Cell biology; Medicine; Biochemistry; Smooth muscle; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001329585,0.0003453701,0.0002233593,0.0001803902,0.0001251666,0.0001734819,0.0001711588,0.0001995218,0.001015497],"category_scores_gemma":[0.0001691385,0.00009738145,0.0001641448,0.000110488,0.0002619722,0.00006665858,0.0001150291,0.0003380909,0.0003274844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002149283,"about_ca_system_score_gemma":0.0002813379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006074819,"about_ca_topic_score_gemma":0.000893186,"domain_scores_codex":[0.999904,0.00002058273,0.00001122769,0.00001430376,0.00002434354,0.00002558493],"domain_scores_gemma":[0.9999195,0.00002465151,0.00001641881,0.000009885211,0.000008788659,0.00002069822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005149032,0.0001691068,0.0001432728,0.00006841581,0.000008510779,0.00004259792,0.00001021762,0.00002922453,0.9970682,0.00003715786,0.00005134052,0.001857079],"study_design_scores_gemma":[0.0003297144,0.002732563,0.007742125,0.00001264846,0.00003750599,0.0002575171,0.00003083512,0.0009503448,0.98568,0.00003742981,0.00218471,0.000004572208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964616,0.001425802,0.0007377068,0.00008093705,0.00004343439,0.00002153733,0.000100503,0.0000598403,0.001068741],"genre_scores_gemma":[0.9954014,0.001280388,0.001239898,0.00005379771,0.00002728151,0.0000406496,0.0002532743,0.00001279176,0.001690427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001015497,"threshold_uncertainty_score":0.003397107,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02091802219908945,"score_gpt":0.240926024164663,"score_spread":0.2200080019655736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}