{"id":"W2014917186","doi":"10.1111/j.1399-3054.2005.00461.x","title":"Progression of programmed cell death in tobacco BY‐2 cells is delineated by specific changes in de novo and salvage synthesis of purine nucleotides","year":2005,"lang":"en","type":"article","venue":"Physiologia Plantarum","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"De novo synthesis; Nucleotide; Purine; Adenine phosphoribosyltransferase; Purine metabolism; Nucleotide salvage; Biochemistry; Programmed cell death; Adenosine; Chemistry; Hydrogen peroxide; Inosine; Biology; Enzyme; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007628369,0.0001992794,0.000233631,0.0001719586,0.0001316958,0.0002984702,0.0001397316,0.0002704843,0.0004246874],"category_scores_gemma":[0.00006283831,0.0001309888,0.0001970356,0.0001625517,0.0001517669,0.0001767552,0.0001223085,0.0003598689,0.0002393238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002104243,"about_ca_system_score_gemma":0.0001709609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007336326,"about_ca_topic_score_gemma":0.0009381639,"domain_scores_codex":[0.9999281,0.000007252481,0.000008595794,0.00002347725,0.00001613183,0.00001652452],"domain_scores_gemma":[0.999887,0.00001866322,0.00003038454,0.00001457339,0.00002218833,0.00002722731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005910044,0.000005881288,0.0004022571,0.00001119494,0.000001235867,0.00003912602,0.00001772707,0.00001316257,0.9990761,0.00003421039,0.000004754366,0.0003353637],"study_design_scores_gemma":[0.00001829626,0.0004044301,0.04911379,0.000007782536,0.00001599342,0.0004271754,0.00008676935,0.001150977,0.9463691,0.0001190742,0.002277064,0.000009568666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946287,0.001765547,0.001829609,0.00002499493,0.00001616992,0.0000248987,0.0004738369,0.00004465851,0.001191608],"genre_scores_gemma":[0.9938652,0.0007644258,0.001680781,0.00003422418,0.000007719149,0.00005044758,0.0009308709,0.00001441082,0.002651954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007336326,"threshold_uncertainty_score":0.001526713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006319490359433112,"score_gpt":0.2545297613187653,"score_spread":0.2482102709593322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}