{"id":"W2014928083","doi":"10.1158/0008-5472.can-04-0729","title":"Phosphorylated Histone H2AX in Spheroids, Tumors, and Tissues of Mice Exposed to Etoposide and 3-Amino-1,2,4-Benzotriazine-1,3-Dioxide","year":2004,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Biology; Etoposide; Molecular biology; Tirapazamine; Cancer research; Biochemistry; In vitro; Cytotoxicity; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006834663,0.0001638753,0.0005014263,0.0003272195,0.00005830024,0.00001832169,0.0001091686,0.00008496426,0.0001946101],"category_scores_gemma":[0.0001649397,0.0001525412,0.00003638964,0.0007925457,0.0002416199,0.00006965669,0.0001265541,0.0003707325,0.000008660752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004771061,"about_ca_system_score_gemma":0.0004633947,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01449742,"about_ca_topic_score_gemma":0.003108552,"domain_scores_codex":[0.9981132,0.00007125638,0.0003601981,0.0004591169,0.0005091578,0.0004871436],"domain_scores_gemma":[0.9989724,0.00009305119,0.00005033883,0.0002922691,0.0002365907,0.0003553446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001317329,0.0001281005,0.004348407,0.0004105238,0.00004657725,0.0001707818,0.001810216,0.00004535707,0.968963,0.0001405405,0.001174497,0.02144466],"study_design_scores_gemma":[0.004944257,0.0007004841,0.01872613,0.0008932654,0.00003590801,0.00003533142,0.000759685,0.000003912919,0.960218,0.0001958243,0.01330211,0.0001850611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9615843,0.0349706,0.00001372043,0.002044961,0.00006571763,0.0007866967,0.00002894982,0.00001898262,0.0004860717],"genre_scores_gemma":[0.9916086,0.00537958,0.00107437,0.0001790517,0.0000947029,0.00009398848,0.000007756887,0.00003594185,0.001525993],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03002431,"threshold_uncertainty_score":0.9920651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06039675301573228,"score_gpt":0.3988629651731032,"score_spread":0.3384662121573709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}