{"id":"W2014928083","doi":"10.1158/0008-5472.can-04-0729","title":"Phosphorylated Histone H2AX in Spheroids, Tumors, and Tissues of Mice Exposed to Etoposide and 3-Amino-1,2,4-Benzotriazine-1,3-Dioxide","year":2004,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Biology; Etoposide; Molecular biology; Tirapazamine; Cancer research; Biochemistry; In vitro; Cytotoxicity; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009390596,0.0004392463,0.0002528013,0.0004730366,0.0001444701,0.000214453,0.0001108874,0.0003131692,0.001540757],"category_scores_gemma":[0.00008373381,0.0002255713,0.0002957549,0.0001627192,0.0002559439,0.000196207,0.0001256315,0.0006463869,0.0003406591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003117896,"about_ca_system_score_gemma":0.0002021447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001096763,"about_ca_topic_score_gemma":0.0009770753,"domain_scores_codex":[0.9999049,0.00001043413,0.000005827563,0.00003165354,0.00002239791,0.00002473319],"domain_scores_gemma":[0.9998728,0.00002001418,0.0000279363,0.00001473978,0.00001139125,0.00005313693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001936988,0.00002757752,0.0003176041,0.00000967473,0.000006887366,0.00004633554,0.00002140842,0.00005902159,0.9989389,0.0000333681,0.00003138956,0.0003141288],"study_design_scores_gemma":[0.00002972261,0.0009717826,0.0132092,0.00000364206,0.00002155269,0.0002372075,0.00005017669,0.001185674,0.9834114,0.0000581916,0.000815756,0.000005775155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954581,0.0006992716,0.001516959,0.00006682372,0.00004410473,0.00003854492,0.0009682252,0.00007882391,0.001129154],"genre_scores_gemma":[0.9907621,0.0006209805,0.001540602,0.00005549863,0.00001459972,0.00007955629,0.001674914,0.0000398001,0.005211937],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001540757,"threshold_uncertainty_score":0.005154312,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06039675301573228,"score_gpt":0.3988629651731032,"score_spread":0.3384662121573709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}