{"id":"W2014967437","doi":"10.1165/rcmb.2009-0392oc","title":"Genetic and Pharmacological Evaluation of Cathepsin S in a Mouse Model of Asthma","year":2010,"lang":"en","type":"article","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Asthma; Cathepsin S; Cathepsin; Computational biology; Medicine; Biology; Bioinformatics; Immunology; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007446308,0.001117114,0.0007924625,0.001077959,0.000496874,0.0006431898,0.0006212267,0.001703524,0.001745096],"category_scores_gemma":[0.000248103,0.0004533419,0.0007514782,0.0004520081,0.00102299,0.000551621,0.0002521718,0.002607661,0.0004965655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006777236,"about_ca_system_score_gemma":0.0006952003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007183925,"about_ca_topic_score_gemma":0.001809986,"domain_scores_codex":[0.999335,0.0001630687,0.00008941984,0.0001227045,0.0001483156,0.0001413882],"domain_scores_gemma":[0.9995384,0.00006157131,0.0001153851,0.00004719774,0.0000391164,0.0001983747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001400995,0.001231482,0.0002258354,0.0001028651,0.00002004132,0.0001508874,0.00003284709,0.0002411169,0.9943362,0.0003955582,0.0001471418,0.00171503],"study_design_scores_gemma":[0.0007568496,0.0121054,0.004182637,0.00003892324,0.000120207,0.0006243054,0.000109249,0.001680126,0.9744067,0.0003031089,0.005644009,0.00002834222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855791,0.003214024,0.00473378,0.0009685937,0.0002325751,0.0004852443,0.001619041,0.0003071234,0.002860442],"genre_scores_gemma":[0.978108,0.003247185,0.007047117,0.0003440976,0.00007532657,0.0009182967,0.001384031,0.00006925631,0.008806657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001745096,"threshold_uncertainty_score":0.005837977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01685217966618593,"score_gpt":0.3147774933619972,"score_spread":0.2979253136958113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}