{"id":"W2015003025","doi":"10.1038/leu.2009.26","title":"Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: high response rates in a phase II clinical trial","year":2009,"lang":"en","type":"article","venue":"Leukemia","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":371,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Cancer Institute","keywords":"Medicine; Dexamethasone; Cyclophosphamide; Bortezomib; Multiple myeloma; Autologous stem-cell transplantation; Internal medicine; Gastroenterology; Surgery; Toxicity; Phases of clinical research; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003452785,0.001594594,0.00380937,0.0005328963,0.0005473293,0.001327769,0.001020745,0.001693323,0.003301446],"category_scores_gemma":[0.002158273,0.0005784472,0.001850309,0.0007717344,0.001202007,0.00105471,0.0004451537,0.004122678,0.0007429707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001268428,"about_ca_system_score_gemma":0.001843594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000960589,"about_ca_topic_score_gemma":0.002414827,"domain_scores_codex":[0.9988376,0.000695459,0.00006006949,0.0001544005,0.00007919688,0.0001733371],"domain_scores_gemma":[0.9980425,0.0006846321,0.0003147779,0.0001757649,0.00006775153,0.0007145888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9027339,0.02111565,0.002263769,0.0004789696,0.001273708,0.0001351337,0.0001251932,0.0009640111,0.008276813,0.0001359681,0.001969206,0.06052765],"study_design_scores_gemma":[0.8703552,0.1220758,0.004519347,0.00002913568,0.0004322506,0.0001226513,0.00002194646,0.0002889032,0.0009042038,0.00009727994,0.001135505,0.00001771886],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871793,0.006164177,0.0005767659,0.001115752,0.0003244101,0.001853777,0.001010668,0.0001116323,0.001663442],"genre_scores_gemma":[0.9873881,0.004027641,0.001558957,0.001322651,0.0004273009,0.001746357,0.001442018,0.00004817011,0.002038728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00380937,"threshold_uncertainty_score":0.01826024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06004671005117541,"score_gpt":0.3975095953405324,"score_spread":0.337462885289357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}