{"id":"W2015003025","doi":"10.1038/leu.2009.26","title":"Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: high response rates in a phase II clinical trial","year":2009,"lang":"en","type":"article","venue":"Leukemia","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":371,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Cancer Institute","keywords":"Medicine; Dexamethasone; Cyclophosphamide; Bortezomib; Multiple myeloma; Autologous stem-cell transplantation; Internal medicine; Gastroenterology; Surgery; Toxicity; Phases of clinical research; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001364448,0.000256363,0.0006688042,0.000235773,0.0001605526,0.00003451868,0.00009053325,0.0002927889,0.0000309156],"category_scores_gemma":[0.006721986,0.0002162758,0.000150249,0.0003245208,0.0001206163,0.0001634442,0.00004302061,0.0004129307,0.00001065021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00045103,"about_ca_system_score_gemma":0.0005855793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004242939,"about_ca_topic_score_gemma":0.00009663782,"domain_scores_codex":[0.9975767,0.000297999,0.0007159333,0.0005873441,0.0002903101,0.0005316758],"domain_scores_gemma":[0.9969276,0.002039902,0.0001456929,0.0003722381,0.0001039872,0.0004105413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6140288,0.002409073,0.02175638,0.00002595974,0.000110327,0.0005592562,0.0002144527,0.000005900174,0.005467028,0.00002923274,0.001085516,0.354308],"study_design_scores_gemma":[0.4827249,0.01652889,0.4913576,0.0000866316,0.00008081678,0.00002755921,0.00006739226,0.001982663,0.004764685,0.0003061279,0.00187237,0.0002003215],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945288,0.0004186902,0.0001605885,0.00142777,0.000263532,0.00305512,0.00003659933,0.00007353099,0.00003538168],"genre_scores_gemma":[0.992181,0.000270131,0.005779338,0.0003842868,0.0004241666,0.0002968951,0.0001396767,0.0000285654,0.0004959198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4696012,"threshold_uncertainty_score":0.8819471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06004671005117541,"score_gpt":0.3975095953405324,"score_spread":0.337462885289357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}