{"id":"W2015006203","doi":"10.1016/j.molmed.2015.01.001","title":"Cancer nanomedicine: from targeted delivery to combination therapy","year":2015,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":687,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; U.S. Public Health Service; National Cancer Institute; Prostate Cancer Foundation; National Institutes of Health; National Heart, Lung, and Blood Institute","keywords":"Nanomedicine; Drug delivery; Cancer therapy; Cancer; Nanotechnology; Nanocarriers; Targeted drug delivery; Medicine; Nanoparticle; Materials science; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007419583,0.0009620737,0.00142451,0.001893451,0.0002529115,0.001232827,0.0009863165,0.001332991,0.002614655],"category_scores_gemma":[0.0006350263,0.000380519,0.0004194553,0.001829605,0.00078977,0.001744727,0.0008847981,0.002574496,0.001606561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007129887,"about_ca_system_score_gemma":0.0008232849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006439608,"about_ca_topic_score_gemma":0.001525375,"domain_scores_codex":[0.9997881,0.0000347371,0.00002124789,0.00004323307,0.00008798603,0.00002476481],"domain_scores_gemma":[0.9997504,0.0001252433,0.00003537147,0.000008615768,0.00005772188,0.00002257677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007438509,0.000131108,0.0001221399,0.0137542,0.00008331013,0.0002006328,0.00006429615,0.0004320931,0.005875559,0.008160794,0.03385467,0.9372469],"study_design_scores_gemma":[0.00001990149,0.0001135723,0.0002899486,0.001931148,0.00006987588,0.001190134,0.00004267661,0.0002358889,0.00192309,0.00255812,0.9916045,0.00002111453],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001247315,0.9979226,0.0004078452,0.0003312368,0.000296081,0.000005794983,0.0000115191,0.000009393797,0.0008907823],"genre_scores_gemma":[0.001211517,0.996822,0.0004981883,0.0003380214,0.000259707,0.0000102375,0.00001982994,0.000003028818,0.0008374419],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002614655,"threshold_uncertainty_score":0.008746862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04598050482459763,"score_gpt":0.3511982488215648,"score_spread":0.3052177439969671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}