{"id":"W2015013205","doi":"10.1002/bies.201100169","title":"Extracellular vesicles – vehicles that spread cancer genes","year":2012,"lang":"en","type":"review","venue":"BioEssays","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":181,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; McGill University; University of Toronto; Montreal Children's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Biology; Multicellular organism; Cell biology; Cancer; Cancer cell; Angiogenesis; Microvesicles; PTEN; Extracellular vesicles; Cancer research; Gene; Signal transduction; Genetics; microRNA; PI3K/AKT/mTOR pathway","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000358045,0.0008106665,0.001034191,0.0001152333,0.0001505073,0.00008304145,0.000910414,0.0009329652,0.0002022449],"category_scores_gemma":[0.00003357924,0.0007022293,0.0008323377,0.0001650241,0.0002557134,0.0000107971,0.0004416371,0.0002913024,0.0002637852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006707029,"about_ca_system_score_gemma":0.0003438053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003199598,"about_ca_topic_score_gemma":0.00001721501,"domain_scores_codex":[0.9970903,0.0002970747,0.0005709681,0.0009302072,0.0003391982,0.0007722068],"domain_scores_gemma":[0.9977286,0.00003944578,0.0004781114,0.001317935,0.00006682387,0.0003690431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001281107,0.0001602187,0.0002022245,0.005276798,0.0003512763,0.00002962844,0.00001137468,8.345135e-7,0.01139983,0.0001743697,0.002662857,0.9797178],"study_design_scores_gemma":[0.0001662571,0.00003509293,0.0000133208,0.001344491,0.001232133,0.00003628158,0.00001352762,0.00000124202,0.009086423,0.00002415753,0.9871901,0.0008570068],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004901545,0.9969016,0.0001338915,0.00001962078,0.0007933528,0.0006857322,0.0004017683,0.00006509661,0.000508763],"genre_scores_gemma":[0.0009628731,0.9908655,0.0004055705,0.00003597517,0.002086149,0.0003440371,0.0009081261,0.0002323339,0.00415938],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9845272,"threshold_uncertainty_score":0.9995429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0667366200197734,"score_gpt":0.327587947729738,"score_spread":0.2608513277099647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}