{"id":"W2015015053","doi":"10.1194/jlr.r400002-jlr200","title":"Genetics of LDL particle heterogeneity","year":2004,"lang":"en","type":"review","venue":"Journal of Lipid Research","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Genetic architecture; Heritability; Genome-wide association study; Biology; Trait; Genetic epidemiology; Disease; Genetic linkage; Genetics; Missing heritability problem; Candidate gene; Quantitative trait locus; Genetic association; Genetic model; Family aggregation; Genetic heterogeneity; Evolutionary biology; Gene; Genetic variants; Medicine; Single-nucleotide polymorphism; Genotype; Phenotype; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005911996,0.0005837604,0.00147594,0.001723515,0.0002168815,0.0009888856,0.0005352948,0.001181488,0.001170113],"category_scores_gemma":[0.0007628506,0.0002154049,0.0002899836,0.001418697,0.0006206766,0.0006995072,0.000440971,0.0008092422,0.0009725764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006725644,"about_ca_system_score_gemma":0.0007982757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001712187,"about_ca_topic_score_gemma":0.00120617,"domain_scores_codex":[0.9997305,0.00005973489,0.00003578982,0.00006848168,0.00008431847,0.00002107276],"domain_scores_gemma":[0.9997442,0.0001162197,0.00004270463,0.00001019317,0.00006448003,0.00002215121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001759755,0.00004936747,0.003859154,0.007776924,0.0002097186,0.001725441,0.0001668033,0.0003658857,0.005703119,0.007708556,0.02408744,0.9481715],"study_design_scores_gemma":[0.00006407079,0.0002003914,0.01881306,0.004931297,0.0004653883,0.02940428,0.000321321,0.0002545209,0.003603857,0.01556368,0.9262969,0.00008117541],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005285389,0.9975277,0.0002758873,0.0005904701,0.0001300259,0.000003102668,0.00001966081,0.000007168682,0.0009175226],"genre_scores_gemma":[0.003575666,0.9950035,0.0003120929,0.0002221551,0.0002410719,0.000005605208,0.00003711785,0.000001877345,0.0006009151],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001723515,"threshold_uncertainty_score":0.004879832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2511238374373066,"score_gpt":0.4966084185549865,"score_spread":0.2454845811176799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}