{"id":"W2015020753","doi":"10.1074/jbc.m114.604082","title":"Nucleoside Triphosphate Diphosphohydrolase-1 Ectonucleotidase Is Required for Normal Vas Deferens Contraction and Male Fertility through Maintaining P2X1 Receptor Function","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Vas deferens; Epididymis; Internal medicine; Endocrinology; Apyrase; Capacitation; Biology; Contraction (grammar); ATP hydrolysis; Receptor; Muscle contraction; Sperm; Andrology; Motility; ATPase; Cell biology; Medicine; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001291228,0.000387623,0.0002085541,0.0002061681,0.0001314657,0.0002964284,0.0002363613,0.0003059708,0.001042061],"category_scores_gemma":[0.0001389803,0.0001439521,0.0001834009,0.00007328111,0.0002425078,0.0001780955,0.0001995114,0.0003237895,0.0002199727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001405573,"about_ca_system_score_gemma":0.0001050765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003888786,"about_ca_topic_score_gemma":0.000492818,"domain_scores_codex":[0.9998691,0.00001757161,0.00001373788,0.00003679494,0.00004106648,0.00002166761],"domain_scores_gemma":[0.9998114,0.0000187687,0.00007669321,0.00001899755,0.00001894046,0.00005531944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005653673,0.000005419222,0.000310064,0.00001973161,0.000002530475,0.0001379953,0.000007331585,0.00001755319,0.9988645,0.00003831469,0.000008142209,0.0005318911],"study_design_scores_gemma":[0.00001690421,0.0003015228,0.0422856,0.000008088799,0.00002351171,0.002071332,0.00004769141,0.0005558587,0.9520077,0.0000762526,0.002599063,0.000006500562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947656,0.001448043,0.002774986,0.0000632467,0.00002203096,0.000009517294,0.0002132161,0.00006024795,0.00064302],"genre_scores_gemma":[0.9949895,0.000741959,0.001442623,0.00002140376,0.00001292386,0.00001271618,0.0003251281,0.00001595142,0.00243781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001042061,"threshold_uncertainty_score":0.003486037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01921559445404119,"score_gpt":0.2485069146317733,"score_spread":0.2292913201777321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}