{"id":"W2015067929","doi":"10.1371/journal.pone.0064449","title":"Antiviral Lectins from Red and Blue-Green Algae Show Potent In Vitro and In Vivo Activity against Hepatitis C Virus","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Hepatitis C virus research","field":"Medicine","cited_by":139,"is_retracted":false,"has_abstract":true,"ca_institutions":"KMT Hepatech (Canada)","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases; U.S. Department of Health and Human Services","keywords":"Boceprevir; Hepatitis C virus; Telaprevir; Virology; Ribavirin; In vivo; Biology; Virus; Alpha interferon; Viral entry; Interferon; Viral replication","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001481731,0.0003456527,0.0001690379,0.0002317452,0.0001135161,0.0001839636,0.000136469,0.0002714707,0.0007351128],"category_scores_gemma":[0.0001032877,0.00008481072,0.0002328926,0.0001541204,0.0002059473,0.000143557,0.0001695858,0.0003794431,0.000255461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001758061,"about_ca_system_score_gemma":0.0001652765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008128227,"about_ca_topic_score_gemma":0.001360595,"domain_scores_codex":[0.9999162,0.0000220473,0.000004400621,0.000009792801,0.00002741751,0.00002009628],"domain_scores_gemma":[0.9999496,0.000009128582,0.000009278298,0.000004661188,0.00001015376,0.00001725165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007504506,0.00003237185,0.000139841,0.00004399689,0.0000052054,0.00002823171,0.000007678233,0.00006559843,0.9972624,0.00004671899,0.00004066285,0.002252286],"study_design_scores_gemma":[0.00002332694,0.0009165072,0.005479247,0.000009445885,0.00001860897,0.000408645,0.00002401043,0.0003982024,0.9878933,0.00006069568,0.004761459,0.000006611866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822363,0.0090121,0.004483222,0.0002103953,0.00005314992,0.00003914976,0.0002655598,0.000105898,0.003594279],"genre_scores_gemma":[0.987104,0.003823158,0.004466235,0.0001933524,0.00002297696,0.00001727642,0.0006959424,0.00001842489,0.003658652],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008128227,"threshold_uncertainty_score":0.002459168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04422045726124673,"score_gpt":0.2627026923904889,"score_spread":0.2184822351292421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}