{"id":"W2015143141","doi":"10.1016/j.mce.2005.06.006","title":"Acute effects of insulin on beta-cells from transplantable human islets","year":2005,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Insulin; Autocrine signalling; Internal medicine; Endocrinology; Insulin receptor; Exocytosis; Islet; Biology; Insulin oscillation; Insulin receptor substrate; Cell biology; Receptor; Insulin resistance; Secretion; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002552056,0.0001651642,0.0004159804,0.0001054963,0.00004211004,0.000005130001,0.00005761196,0.00009374174,0.0001724558],"category_scores_gemma":[0.000008669808,0.0001458081,0.0001026743,0.00006243763,0.00008946562,0.00002059334,0.00001916767,0.0001597399,0.00006315178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001404327,"about_ca_system_score_gemma":0.0000155626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005347738,"about_ca_topic_score_gemma":0.000001064762,"domain_scores_codex":[0.999046,0.00006010757,0.0002119951,0.0002730166,0.0001306263,0.0002782872],"domain_scores_gemma":[0.9994887,0.00006966961,0.00005038065,0.0002616009,0.00002290061,0.0001067231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001205793,0.0002118629,0.0003305715,0.00007482698,0.0002910096,0.0004829416,0.00007900276,0.000006980365,0.9941211,0.001414159,0.0001740796,0.002692835],"study_design_scores_gemma":[0.003565066,0.0006362769,0.0004364461,0.00005450692,0.000491032,0.00002821365,0.000009829385,0.00005436272,0.9885144,0.0001376602,0.005955669,0.0001165619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990425,0.002783991,0.0008100495,0.0002950465,0.0001042486,0.0002175015,0.00001630698,0.00004131726,0.00530654],"genre_scores_gemma":[0.9975753,0.00019076,0.0004639842,0.001063168,0.00005826996,0.00001466829,0.00008922716,0.0000188416,0.0005258094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007150273,"threshold_uncertainty_score":0.5945883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006108296843848121,"score_gpt":0.2231387025027744,"score_spread":0.2170304056589263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}