{"id":"W2015148142","doi":"10.1002/ijc.27918","title":"Cytotoxic and immune‐mediated killing of human colorectal cancer by reovirus‐loaded blood and liver mononuclear cells","year":2012,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"National Cancer Institute; Cancer Research UK","keywords":"Cytotoxic T cell; Oncolytic virus; Immune system; Peripheral blood mononuclear cell; Innate immune system; Immunology; NK-92; Biology; Virus; Virology; Cancer cell; Cancer; Natural killer T cell; CD8; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002349737,0.00009637979,0.000145257,0.00007560731,0.00003378728,0.00001873131,0.0001842052,0.00008105698,0.0001474187],"category_scores_gemma":[0.00001804677,0.0000869077,0.00005640744,0.00003627239,0.000110409,0.00001731788,0.00007120194,0.000136527,7.929079e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003245137,"about_ca_system_score_gemma":0.00007792644,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001497674,"about_ca_topic_score_gemma":0.00005764875,"domain_scores_codex":[0.9991471,0.00005163804,0.0002678811,0.0001025486,0.0002739314,0.0001569197],"domain_scores_gemma":[0.9993028,0.00002090394,0.0002457669,0.00005740775,0.0002721035,0.000101012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001065893,0.00007662377,0.005694598,0.000008561504,0.0004912225,0.000003622188,0.0001582564,0.00002435159,0.989917,0.000003826346,0.0003290799,0.00222698],"study_design_scores_gemma":[0.001234867,0.0006306773,0.002762459,0.00004335112,0.00003903987,0.00001922767,0.00003450671,0.0000200508,0.9937049,0.00001062312,0.001409846,0.00009050413],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9680268,0.03146685,0.00001636732,0.0001045194,0.0002106999,0.00006275467,0.00007144682,0.000001601515,0.00003895214],"genre_scores_gemma":[0.9877214,0.0116189,0.00004572119,0.0001068435,0.0004025356,0.000005797274,0.00000789219,0.00001785522,0.00007302501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01984794,"threshold_uncertainty_score":0.3543993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01190299017785677,"score_gpt":0.3097231313980809,"score_spread":0.2978201412202242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}