{"id":"W2015148142","doi":"10.1002/ijc.27918","title":"Cytotoxic and immune‐mediated killing of human colorectal cancer by reovirus‐loaded blood and liver mononuclear cells","year":2012,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"National Cancer Institute; Cancer Research UK","keywords":"Cytotoxic T cell; Oncolytic virus; Immune system; Peripheral blood mononuclear cell; Innate immune system; Immunology; NK-92; Biology; Virus; Virology; Cancer cell; Cancer; Natural killer T cell; CD8; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001429316,0.0002044106,0.0001982447,0.00008795894,0.00007334557,0.0002165373,0.00008333829,0.0001444197,0.0009826022],"category_scores_gemma":[0.0001566613,0.00006365614,0.0001268785,0.00005943397,0.0001424194,0.0001240195,0.0001146954,0.0001615842,0.000232254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001640221,"about_ca_system_score_gemma":0.0001373181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00069292,"about_ca_topic_score_gemma":0.0007185428,"domain_scores_codex":[0.9998986,0.00003318397,0.000005889251,0.00001952477,0.00001664472,0.00002618964],"domain_scores_gemma":[0.9999498,0.00001720798,0.000007812441,0.00000945163,0.000007709644,0.00000796826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003677509,0.00003068488,0.0002392513,0.00005121788,0.00000342316,0.00004646447,0.0000355696,0.0001004309,0.9960989,0.00007026807,0.00002359889,0.002932444],"study_design_scores_gemma":[0.00006854936,0.001802279,0.003918971,0.00000870235,0.00002296948,0.0004446409,0.00004024674,0.001069145,0.9907268,0.00003884769,0.001853211,0.000005656228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963751,0.001307805,0.00136413,0.00001991663,0.00001068128,0.00002012434,0.00004291784,0.0000154132,0.0008438546],"genre_scores_gemma":[0.9971262,0.0004359398,0.00112177,0.00001933662,0.000006166908,0.00002233786,0.00009955258,0.000005643315,0.001163041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009826022,"threshold_uncertainty_score":0.003287137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01190299017785677,"score_gpt":0.3097231313980809,"score_spread":0.2978201412202242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}