{"id":"W2015181181","doi":"10.1021/pr900788a","title":"Activity-Based Proteome Profiling of Hepatoma Cells during Hepatitis C Virus Replication Using Protease Substrate Probes","year":2009,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Hepatitis C virus research","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Steacie Institute for Molecular Sciences; University of Ottawa","funders":"Canadian Institutes of Health Research; Canadian Liver Foundation","keywords":"Biochemistry; Protease; Biology; Proteome; Hepatitis C virus; Molecular biology; Enzyme; Chemistry; Virus; Virology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001258797,0.0002306087,0.0001989571,0.0001750679,0.0001267114,0.0002119749,0.00008714402,0.0001698975,0.0004666212],"category_scores_gemma":[0.0001242341,0.0001161018,0.0001222511,0.000185841,0.0001191955,0.0001464817,0.00011566,0.000300299,0.000222729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001391516,"about_ca_system_score_gemma":0.00006746146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003301634,"about_ca_topic_score_gemma":0.0005035863,"domain_scores_codex":[0.9999146,0.00001761441,0.000005751855,0.00002062897,0.00002499336,0.00001632814],"domain_scores_gemma":[0.9998935,0.0000415515,0.00001977288,0.00001064096,0.00002038651,0.00001405004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003852906,0.00000317148,0.0002202142,0.00000813753,0.000001605919,0.00001033197,0.000008985015,0.0000172055,0.999203,0.00001238969,0.000004767134,0.000471794],"study_design_scores_gemma":[0.00000288077,0.00008638034,0.006483195,0.000001189525,0.000007123687,0.0001085353,0.00002053514,0.0006818766,0.9922842,0.00001949886,0.0003018108,0.000002790299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905879,0.0005579344,0.007599632,0.00003192926,0.000009417913,0.00002244418,0.000330914,0.000063242,0.000796441],"genre_scores_gemma":[0.9870259,0.0007635069,0.009871034,0.00004167357,0.000006702084,0.00004502217,0.0009386872,0.00002177391,0.001285702],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004666212,"threshold_uncertainty_score":0.001560986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1216002455539903,"score_gpt":0.4255431243797151,"score_spread":0.3039428788257248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}