{"id":"W2015192421","doi":"10.1016/j.cell.2007.09.029","title":"Retrovirus Silencing by an Epigenetic TRIM","year":2007,"lang":"en","type":"letter","venue":"Cell","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Biology; Retrovirus; Gene silencing; Epigenetics; Trim; Virology; Genetics; Computational biology; Virus; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0004560372,0.0004152654,0.0003036665,0.0001327542,0.0001050705,0.00005668872,0.00074187,0.001402501,0.0002382596],"category_scores_gemma":[0.00002686194,0.0004327823,0.0001854207,0.0001300956,0.0001298029,0.000002483856,0.0001268737,0.00112982,0.0002996098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006333727,"about_ca_system_score_gemma":0.00024306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005165776,"about_ca_topic_score_gemma":0.00003485692,"domain_scores_codex":[0.9973136,0.0002026695,0.000320545,0.0008832382,0.0004511731,0.0008287957],"domain_scores_gemma":[0.9983796,0.00002868926,0.0001324322,0.001185979,0.0001086827,0.000164633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001607021,0.00002626764,0.0000067034,0.00004126757,0.00001987163,0.00004880768,0.00001029372,0.00000349099,0.5154328,2.234275e-8,0.4830759,0.001173788],"study_design_scores_gemma":[0.0003441279,0.001761271,0.000002504114,0.000006846548,0.00001348547,0.00000413485,0.000007127643,0.000004631832,0.5392161,0.000009145307,0.4583423,0.0002883816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.9077328,0.03117627,0.002178973,0.03579552,0.001275155,0.001601538,0.0005563365,0.0001353363,0.01954809],"genre_scores_gemma":[0.06817562,0.002366704,0.0005658994,0.8415229,0.01514732,0.00009222489,0.008911724,0.0005990039,0.06261862],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8395572,"threshold_uncertainty_score":0.9998939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01923808000610933,"score_gpt":0.2881219474771817,"score_spread":0.2688838674710724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}