{"id":"W2015254928","doi":"10.1186/1742-4690-6-s2-p47","title":"Inhibition of HIV-1 expression and replication by SOFA-HDV ribozymes against Tat and Rev mRNA sequences","year":2009,"lang":"en","type":"article","venue":"Retrovirology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; McGill University","funders":"","keywords":"Ribozyme; Retrovirus; Human immunodeficiency virus (HIV); Virology; Replication (statistics); Messenger RNA; Library science; Medicine; Biology; RNA; Virus; Gene; Genetics; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002005235,0.0001084936,0.0002121664,0.00008018813,0.0001094646,0.000006209675,0.00005274664,0.0002039118,0.00006140006],"category_scores_gemma":[0.00009748775,0.00008676574,0.00002452197,0.00005548541,0.0003282847,0.00007919838,0.0000363123,0.0001475901,0.00004627256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001975756,"about_ca_system_score_gemma":0.00001882987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001873704,"about_ca_topic_score_gemma":0.000003323938,"domain_scores_codex":[0.9990034,0.0001976315,0.0002115181,0.000331294,0.00003062315,0.0002255143],"domain_scores_gemma":[0.9995005,0.00008822982,0.0001146264,0.0002326882,0.00003121596,0.00003274881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001391031,0.00007105776,0.01248045,0.00001117572,0.00002150329,0.00000509116,0.0001196038,2.555259e-7,0.9603651,0.000175865,0.005171563,0.02143929],"study_design_scores_gemma":[0.002378512,0.002004456,0.04703043,0.0000523223,0.00003045876,0.0001021832,0.0001117211,0.000007409795,0.9320102,0.001116429,0.01498603,0.0001698409],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888995,0.008626563,0.00006761417,0.001397595,0.0000277382,0.0001804037,0.0001040145,0.00002716044,0.0006693799],"genre_scores_gemma":[0.996321,0.002292127,0.0001585928,0.0001815936,0.0000105135,0.00001333647,0.000532645,0.000004672563,0.0004855119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03454999,"threshold_uncertainty_score":0.3538204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009633900251026959,"score_gpt":0.2529898958478521,"score_spread":0.2433559955968251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}