{"id":"W2015268376","doi":"10.1007/s00280-011-1679-8","title":"Hematologic adverse events associated with temozolomide","year":2011,"lang":"en","type":"article","venue":"Cancer Chemotherapy and Pharmacology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Pancytopenia; Medicine; Aplastic anemia; Internal medicine; Adverse effect; Myelodysplastic syndromes; Temozolomide; Bone marrow suppression; Bone marrow failure; Bone Marrow Aplasia; Pediatrics; Surgery; Bone marrow; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004232103,0.0001364351,0.0002555153,0.0001663066,0.0001894716,0.0001787242,0.0001265062,0.0001450246,0.001281378],"category_scores_gemma":[0.001372871,0.00005295344,0.0003148333,0.0002886763,0.0001007657,0.0001182786,0.0001507572,0.0005670911,0.0000949512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004194919,"about_ca_system_score_gemma":0.0002893123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001226444,"about_ca_topic_score_gemma":0.003864735,"domain_scores_codex":[0.9997191,0.0001280004,0.00003364295,0.00001377564,0.00007984095,0.00002565422],"domain_scores_gemma":[0.9992552,0.0002497555,0.0003044977,0.00003167168,0.00008295594,0.00007590948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.02330428,0.001276614,0.2477126,0.00155597,0.001687616,0.009939558,0.00020823,0.002154461,0.1019811,0.001146766,0.005893134,0.6031396],"study_design_scores_gemma":[0.001071629,0.01178479,0.8914546,0.0001604575,0.0009819947,0.0228905,0.0001603556,0.002323826,0.03510751,0.0004411848,0.03359559,0.00002760517],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9754612,0.01238951,0.001667804,0.000426324,0.00006814882,0.0001019287,0.0004660086,0.00005623048,0.009362795],"genre_scores_gemma":[0.9956727,0.002050664,0.0006435492,0.0002375466,0.00004261427,0.00002508525,0.0002001458,0.000005779381,0.001122035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001281378,"threshold_uncertainty_score":0.004286647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04505727237691332,"score_gpt":0.3367991244967081,"score_spread":0.2917418521197948,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}