{"id":"W2015364707","doi":"10.1101/gr.171439.113","title":"The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes","year":2014,"lang":"en","type":"article","venue":"Genome Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":362,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; McGill University; Douglas Mental Health University Institute; University of British Columbia","funders":"National Research Foundation; National Medical Research Council; National Research Foundation Singapore; National Institute for Health and Care Research; Agency for Science, Technology and Research; Medical Research Council; Canadian Institute for Advanced Research","keywords":"DNA methylation; Biology; Epigenetics; Genetics; Genotype; In utero; Methylation; Genetic variation; DNA; Fetus; Gene; Pregnancy; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0028774,0.00006370828,0.00008628213,0.0001017312,0.00004529383,0.00001617699,0.0001183882,0.0000709216,0.000004701951],"category_scores_gemma":[0.0001757162,0.00004663632,0.00001705254,0.00007544211,0.00007070706,0.00000151781,0.0001391652,0.0001139224,0.000004857846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002247022,"about_ca_system_score_gemma":0.00001109647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003966269,"about_ca_topic_score_gemma":0.00004515923,"domain_scores_codex":[0.9987108,0.0005731905,0.0001464271,0.0001942039,0.0001846423,0.0001907549],"domain_scores_gemma":[0.9995286,0.000187293,0.00002953804,0.0002097983,0.00001523615,0.00002956861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001983838,0.00001493913,0.004792904,0.00001650765,0.00001186306,7.577984e-7,0.0001271118,0.0004671198,0.9590487,0.00005732533,0.000001487144,0.03526285],"study_design_scores_gemma":[0.00076298,0.001948081,0.4270773,0.000009637649,0.000002828101,4.467933e-7,0.00001792221,0.0002878175,0.5559298,0.0006227497,0.01325245,0.00008800039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976156,0.001449128,0.0002789129,0.00009947825,0.00002236591,0.0002063747,0.000002740178,7.899208e-7,0.0003245891],"genre_scores_gemma":[0.9984761,0.001259336,0.00009925805,0.000004287656,0.00003690033,0.00002647246,0.00001246068,0.000007929416,0.00007726822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4222844,"threshold_uncertainty_score":0.1901774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01671615804003995,"score_gpt":0.3084512473536649,"score_spread":0.291735089313625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}