{"id":"W2015384574","doi":"10.1016/s0959-440x(00)00131-7","title":"High-throughput protein crystallization","year":2000,"lang":"en","type":"review","venue":"Current Opinion in Structural Biology","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":235,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"University of Toronto","keywords":"Throughput; Protein crystallization; Computer science; Nanotechnology; Combinatorial synthesis; Beamline; Crystallization; Chemistry; Materials science; Combinatorial chemistry; Physics; Operating system; Optics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001643366,0.0005401935,0.001284985,0.0002715762,0.0001078944,0.00005750276,0.0004299349,0.0005783552,0.002128331],"category_scores_gemma":[0.00005053838,0.0003870123,0.0002085526,0.0004104109,0.0001753483,0.0001630105,0.0001119107,0.0004981527,0.0002400014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001780953,"about_ca_system_score_gemma":0.0001590922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004448196,"about_ca_topic_score_gemma":0.000005350018,"domain_scores_codex":[0.9971123,0.0004605549,0.0009512082,0.0008451233,0.0001508947,0.0004799014],"domain_scores_gemma":[0.9989402,0.00006310952,0.0004618403,0.0004168773,0.00004574388,0.00007227722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001553028,0.00000810752,0.00000443911,0.005819423,0.000008829867,3.798498e-7,0.0000278717,0.000007317183,0.0001904765,0.008192185,0.0005194885,0.9852059],"study_design_scores_gemma":[0.0002317854,0.00008030227,0.000009488913,0.003904043,0.00003146072,0.00002439247,0.000002168212,0.000003637488,0.00003891387,0.004501895,0.9907371,0.0004347597],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002992273,0.9797032,0.0001531404,0.00001108307,0.01833112,0.001036049,0.0002658151,0.0001070547,0.00009328629],"genre_scores_gemma":[0.0001721808,0.9943739,0.0004067694,0.000005591603,0.002039037,0.000176865,0.002748672,0.00003726,0.00003968037],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9902177,"threshold_uncertainty_score":0.9998582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06741474078615106,"score_gpt":0.3750236206787462,"score_spread":0.3076088798925951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}