{"id":"W2015406424","doi":"10.1073/pnas.1111501108","title":"Promoter regulation by distinct mechanisms of functional interplay between lysine acetylase Rtt109 and histone chaperone Asf1","year":2011,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; Canadian Institutes of Health Research; Government of Alberta; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; University of Alberta","keywords":"Histone H3; Acetylation; Lysine; Histone; Chromatin immunoprecipitation; Transcription (linguistics); Cell biology; Chromatin; Transcriptional regulation; Biology; Chemistry; Gene; Transcription factor; Promoter; Biochemistry; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002799381,0.0004232174,0.0004752129,0.0002311141,0.0001449457,0.0007063025,0.0003313241,0.0003152481,0.0007136223],"category_scores_gemma":[0.0002695174,0.0002179031,0.0004453014,0.00015916,0.0003976238,0.0004207374,0.0005285688,0.0004567361,0.000462782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000498852,"about_ca_system_score_gemma":0.0002094697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004235677,"about_ca_topic_score_gemma":0.0005082526,"domain_scores_codex":[0.9996532,0.00004946258,0.00003241513,0.000106253,0.00008659415,0.00007198583],"domain_scores_gemma":[0.9997528,0.00003362147,0.0000679302,0.00003674519,0.00003942179,0.00006938616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007796125,0.00001106167,0.0005282441,0.00001690032,0.000005551937,0.0000362531,0.00001144471,0.00007110154,0.9983444,0.0001434917,0.00002003794,0.0007334633],"study_design_scores_gemma":[0.00002263664,0.0001013769,0.01369437,0.000005187276,0.00002019872,0.0002794675,0.00005963522,0.003590109,0.9805388,0.0001616243,0.001514309,0.00001220539],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916202,0.001526848,0.005206943,0.0001149766,0.00003402309,0.00001204302,0.0001680201,0.0001454092,0.001171571],"genre_scores_gemma":[0.9964318,0.0003068994,0.001750662,0.00003129926,0.000009486239,0.00002000724,0.0003269159,0.00003049175,0.001092466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007136223,"threshold_uncertainty_score":0.003619373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04160485399803923,"score_gpt":0.3116389798919559,"score_spread":0.2700341258939167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}