{"id":"W2015409073","doi":"10.1007/s00251-005-0785-3","title":"Evolution of transcriptional enhancers in the immunoglobulin heavy-chain gene: functional characteristics of the zebrafish E?3? enhancer","year":2005,"lang":"en","type":"article","venue":"Immunogenetics","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Enhancer; Biology; Zebrafish; Immunoglobulin heavy chain; Gene; Genetics; Human genetics; Enhancer RNAs; Computational biology; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002692811,0.0001798988,0.0002388394,0.0005172236,0.0003608973,0.0003078273,0.000340846,0.000466139,0.001350862],"category_scores_gemma":[0.0003121819,0.0003180605,0.0003306057,0.0001939676,0.0004482154,0.0002329108,0.0005159117,0.0007093439,0.0004172086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006528035,"about_ca_system_score_gemma":0.0002901857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002792692,"about_ca_topic_score_gemma":0.005215344,"domain_scores_codex":[0.9998757,0.00001017254,0.000006305441,0.00003867895,0.00003626859,0.00003293223],"domain_scores_gemma":[0.9997981,0.00005532003,0.00003713586,0.00002951707,0.00003648409,0.00004342624],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005802676,0.000009164179,0.001864458,0.00001521453,0.000003650177,0.00009778377,0.00006388333,0.0001681792,0.993572,0.000726571,0.00002617205,0.00339488],"study_design_scores_gemma":[0.00009089465,0.0002481953,0.3764794,0.00006309173,0.00008185493,0.003325116,0.0002779583,0.007120747,0.5947622,0.00208567,0.01539718,0.00006764708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904106,0.0004665671,0.005215812,0.0001196605,0.000008533626,0.00001497037,0.0001542974,0.00006252329,0.003547051],"genre_scores_gemma":[0.9937983,0.0002231851,0.002610919,0.0001180624,0.00000714976,0.00001353669,0.0002709535,0.0000521139,0.002905718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002792692,"threshold_uncertainty_score":0.005552948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005131135231955341,"score_gpt":0.1987750880448348,"score_spread":0.1936439528128795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}