{"id":"W2015584982","doi":"10.1083/jcb.200808064","title":"A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling","year":2009,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Heart, Lung, and Blood Institute","keywords":"Endocytic cycle; Biology; Cell biology; Bone morphogenetic protein; BMPR2; Signal transduction; Endocytosis; Noggin; SMAD; Internalization; Crosstalk; Activator (genetics); Biochemistry; Cell; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":{"n_in":0,"stratum":"aff_core","weight":5595.2375,"opus":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"Cell-biology study of Bmper endocytic regulation of Bmp signaling; the object is a molecular mechanism."},"gpt":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"The study investigates molecular signaling mechanisms rather than how research is conducted or communicated."},"grok":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"Molecular cell-biology study of Bmper and Bmp signaling mechanisms."}}}