{"id":"W2015645387","doi":"10.1038/mt.2010.26","title":"Transcriptional and Translational Dual-regulated Oncolytic Herpes Simplex Virus Type 1 for Targeting Prostate Tumors","year":2010,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"Terry Fox Foundation","keywords":"Oncolytic virus; Herpes simplex virus; Virology; Cancer research; Biology; Virus; Dual (grammatical number)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003170755,0.0002233506,0.0001679011,0.0000652197,0.0001631443,0.00005105217,0.0001450139,0.0001513677,0.00009552739],"category_scores_gemma":[0.00002789844,0.0002152861,0.0001157214,0.0001371961,0.0001501349,0.000007747124,0.00001534013,0.0001422666,0.000005418401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005941673,"about_ca_system_score_gemma":0.0001701814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009826914,"about_ca_topic_score_gemma":0.0001041622,"domain_scores_codex":[0.9986402,0.00008229852,0.0002373158,0.0004359715,0.0002367139,0.0003675076],"domain_scores_gemma":[0.9993644,0.00002234009,0.00005514687,0.0002376262,0.0001954195,0.0001250125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003259378,0.0001020037,0.0001472809,0.00001217111,0.0001147681,0.000005334176,0.000112885,0.0001616093,0.9681711,0.000151057,0.000167873,0.02759456],"study_design_scores_gemma":[0.002594765,0.001581876,0.00195363,0.000004847867,0.00001013645,0.00001332901,0.00001474319,0.0006505388,0.9283107,0.001005424,0.06355281,0.000307178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956536,0.001663418,0.0009711209,0.0007006172,0.00009981962,0.0007513722,0.00009261794,0.00002666958,0.0000407401],"genre_scores_gemma":[0.9965363,0.0002003768,0.001510026,0.0005690495,0.0001753847,0.00009773076,0.0006316479,0.00007067622,0.0002088594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06338494,"threshold_uncertainty_score":0.8779112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01586924130199208,"score_gpt":0.2970149210796898,"score_spread":0.2811456797776977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}