{"id":"W2015775599","doi":"10.1042/bst0300755","title":"The role of oxidative stress in the toxicity of pyridoxal isonicotinoyl hydrazone (PIH) analogues","year":2002,"lang":"en","type":"article","venue":"Biochemical Society Transactions","topic":"Pesticide Exposure and Toxicity","field":"Agricultural and Biological Sciences","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Oxidative stress; Toxicity; Glutathione; Chemistry; Biochemistry; Lipid peroxidation; Jurkat cells; Reactive oxygen species; Antioxidant; Pharmacology; Biology; Enzyme; Immunology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002344897,0.0002811232,0.000334718,0.0001954113,0.0002081102,0.0003096274,0.0001513948,0.0004315093,0.000719365],"category_scores_gemma":[0.0002318336,0.0001550047,0.0001762114,0.00013848,0.0002278079,0.0002064841,0.0001505518,0.0003035424,0.0001510451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002853996,"about_ca_system_score_gemma":0.0001731521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006415335,"about_ca_topic_score_gemma":0.0007135981,"domain_scores_codex":[0.999862,0.00003841573,0.00002026451,0.0000186063,0.00003333462,0.00002737892],"domain_scores_gemma":[0.999835,0.00003007476,0.00004478469,0.00002082864,0.00003825402,0.00003103133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003215565,0.0000214365,0.0003213563,0.00004601731,0.000005934126,0.0001735422,0.00002081397,0.00009981346,0.9971253,0.00007932681,0.00002086129,0.001764085],"study_design_scores_gemma":[0.00002020442,0.0005964019,0.004785778,0.000005850798,0.00001652037,0.0003998192,0.00002436055,0.0002994977,0.9925223,0.00006129107,0.00126471,0.000003293397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942894,0.002892007,0.001467945,0.0001398579,0.00001894844,0.00002727896,0.0001101372,0.00002794685,0.001026472],"genre_scores_gemma":[0.99634,0.001320895,0.001205034,0.00003796842,0.000008679376,0.00001223792,0.0001202932,0.000004597324,0.0009503284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000719365,"threshold_uncertainty_score":0.002406538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01441686879187425,"score_gpt":0.2051620144796652,"score_spread":0.1907451456877909,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}