{"id":"W2015795764","doi":"10.1016/j.brainres.2010.05.054","title":"Chronic buspirone treatment decreases 5-HT1B receptor densities and the serotonin transporter but increases the density of 5-HT2A receptors in the bulbectomized rat model of depression: an autoradiographic study","year":2010,"lang":"en","type":"article","venue":"Brain Research","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Buspirone; Serotonergic; Serotonin; 5-HT receptor; Internal medicine; Endocrinology; Agonist; Receptor; Ketanserin; Antidepressant; Chemistry; Saline; Medicine; Hippocampus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.004265181,0.0003657872,0.0006211099,0.0003999763,0.0006250681,0.0001477383,0.001424676,0.0001368854,0.0001439123],"category_scores_gemma":[0.0008364373,0.0001780811,0.0002019068,0.001046021,0.003711816,0.0003067709,0.0001293371,0.0009783744,0.000004373606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006422374,"about_ca_system_score_gemma":0.0003389615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005029341,"about_ca_topic_score_gemma":0.003801759,"domain_scores_codex":[0.9913664,0.005011117,0.0006899684,0.0008097249,0.001470549,0.0006522093],"domain_scores_gemma":[0.9936836,0.004296963,0.0001949655,0.001474321,0.0001807422,0.0001693623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002421475,0.001694059,0.1311819,0.00004569963,0.00002448667,0.00004092279,0.0100991,0.0001022607,0.8502551,0.0003076348,0.0001146831,0.003712655],"study_design_scores_gemma":[0.01527081,0.002377933,0.1237675,0.0001416289,0.0001607848,0.0001373091,0.006940265,0.003024271,0.846965,0.0004270785,0.0002688323,0.000518596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934852,0.0001617724,0.000007584717,0.001501771,0.0001020931,0.004634316,0.00004570212,0.00004145383,0.00002009897],"genre_scores_gemma":[0.9984362,0.0001846479,0.00007645765,0.0001567597,0.00007062971,0.0009095155,0.000004457185,0.0000460947,0.0001152314],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01284934,"threshold_uncertainty_score":0.9989995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07840230299228745,"score_gpt":0.3541883354422123,"score_spread":0.2757860324499249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}