{"id":"W2015820044","doi":"10.1021/bi0007728","title":"Specificity and Affinity of Substrate Binding by a Family 17 Carbohydrate-Binding Module from <i>Clostridium cellulovorans</i> Cellulase 5A","year":2000,"lang":"en","type":"article","venue":"Biochemistry","topic":"Polysaccharides and Plant Cell Walls","field":"Agricultural and Biological Sciences","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Carbohydrate-binding module; Cellulase; Chemistry; Tryptophan; Binding site; Ligand (biochemistry); Stereochemistry; Quenching (fluorescence); Biochemistry; Cellulose; Affinities; Fluorescence; Amino acid; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001645476,0.0002834087,0.0002020471,0.0001781327,0.0001112843,0.0003728543,0.0003051909,0.0002806642,0.001991258],"category_scores_gemma":[0.0004362435,0.0001552625,0.0002600597,0.0001509541,0.0001456728,0.0001615433,0.0002330661,0.0003214378,0.0007575243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003906026,"about_ca_system_score_gemma":0.0001039478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001498491,"about_ca_topic_score_gemma":0.00083233,"domain_scores_codex":[0.9996644,0.00006109216,0.00001429538,0.00006931296,0.00008492499,0.0001058661],"domain_scores_gemma":[0.9998203,0.00005906623,0.00003223652,0.00001067616,0.00003248877,0.00004528825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000121514,0.00002515689,0.003038243,0.00005569885,0.0000158917,0.00002196162,0.00002089043,0.0001339149,0.9932947,0.00007329285,0.00009440212,0.003104449],"study_design_scores_gemma":[0.000008746175,0.0002819921,0.05332702,0.00001907176,0.00002595103,0.0005982996,0.00004668598,0.003213594,0.9394044,0.0000501419,0.003008861,0.00001516476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952877,0.001456459,0.001743428,0.00002980758,0.00000844594,0.000007250962,0.0001685935,0.00002971242,0.001268737],"genre_scores_gemma":[0.9964724,0.0003273116,0.001425941,0.00004112996,0.000003851117,0.000009569019,0.0007168663,0.00001505243,0.0009879145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001991258,"threshold_uncertainty_score":0.006661475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01217976644171536,"score_gpt":0.1781799169106523,"score_spread":0.1660001504689369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}