{"id":"W2015828638","doi":"10.3892/ijo.2014.2297","title":"Feroniellin A-induced autophagy causes apoptosis in multidrug-resistant human A549 lung cancer cells","year":2014,"lang":"en","type":"article","venue":"International Journal of Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":37,"is_retracted":true,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Division of Chemistry; Office of the Higher Education Commission; Korea Research Institute of Bioscience and Biotechnology; National Research Foundation","keywords":"Biology; Apoptosis; Autophagy; Downregulation and upregulation; Multiple drug resistance; Cancer cell; Cancer research; ATG5; Programmed cell death; Cell biology; Multidrug resistance-associated protein 2; PI3K/AKT/mTOR pathway; Cancer; Drug resistance; ATP-binding cassette transporter; Biochemistry; Gene; Microbiology; Transporter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":{"nature":"Retraction","reason":"Concerns/Issues about Data;Duplication of Data;Investigation by Journal/Publisher;Investigation by Third Party;Unreliable Data;","date":"3/4/2025 0:00","openalex_flagged":true},"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001498287,0.0003162134,0.0003949636,0.0003017172,0.000217391,0.0001766698,0.0001121124,0.0003095377,0.001144871],"category_scores_gemma":[0.00008583925,0.0001283885,0.000444248,0.000282368,0.0001373468,0.0001780795,0.0001243033,0.0004437461,0.0003034637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002962101,"about_ca_system_score_gemma":0.0001550351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001117193,"about_ca_topic_score_gemma":0.0009788708,"domain_scores_codex":[0.9998839,0.00001816566,0.00001542767,0.00002512776,0.00002861089,0.00002883776],"domain_scores_gemma":[0.9999524,0.00001011713,0.00001051433,0.000007560523,0.000008437641,0.00001097619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002715426,0.00006831545,0.0002122836,0.00004856378,0.00001042155,0.0001411964,0.00002581233,0.0000673332,0.9976081,0.00006294703,0.00008224456,0.001401222],"study_design_scores_gemma":[0.00008853213,0.001141668,0.009230685,0.0000107334,0.00002771049,0.0006492338,0.0000494769,0.001277607,0.9842963,0.00008127932,0.003137813,0.000008968902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918072,0.003856666,0.001625348,0.0001632443,0.00005262607,0.00005964009,0.0006281956,0.00008720771,0.00171996],"genre_scores_gemma":[0.9941473,0.001522749,0.00110447,0.00009267292,0.00001829365,0.00005409663,0.001028761,0.000008384754,0.002023336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001144871,"threshold_uncertainty_score":0.003830016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02445358979184263,"score_gpt":0.3870455390492786,"score_spread":0.3625919492574359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}