{"id":"W2015833555","doi":"10.1208/aapsj070357","title":"Mucosal delivery of bacterial antigens and CpG oligonucleotides formulated in biphasic lipid vesicles in pigs","year":2005,"lang":"en","type":"article","venue":"The AAPS Journal","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Oligonucleotide; Lipid vesicle; Vesicle; Antigen; CpG Oligodeoxynucleotide; Chemistry; Biology; Molecular biology; Microbiology; Immunology; DNA; Biochemistry; Gene; DNA methylation; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002770474,0.0001025041,0.0001410422,0.00008610573,0.00005061327,0.0000285011,0.0001793142,0.00007599589,0.00005010145],"category_scores_gemma":[0.00002640772,0.00007513355,0.000052509,0.00007183447,0.0000732218,0.00001522424,0.00007496645,0.0001430609,0.000004224651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001179439,"about_ca_system_score_gemma":0.00005274804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004450824,"about_ca_topic_score_gemma":0.0003098531,"domain_scores_codex":[0.9992372,0.00007048628,0.000297851,0.0001198718,0.00007579476,0.0001988195],"domain_scores_gemma":[0.9996644,0.00001323192,0.000101289,0.000130301,0.0000478822,0.00004287529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003146361,0.00004287199,0.01521201,0.000005169535,0.00002672786,0.000007852617,0.0002805008,0.000139246,0.9698498,0.00001096178,0.0004983017,0.01361192],"study_design_scores_gemma":[0.00269625,0.000669757,0.2653355,0.0001315301,0.00002776606,0.0003914661,0.0005394045,0.000522616,0.7261328,0.0002602352,0.002990454,0.0003022206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984824,0.001031636,0.00001758291,0.0001948997,0.0001021429,0.0000596162,0.000006793989,0.000002043093,0.0001028774],"genre_scores_gemma":[0.9973099,0.002017469,0.0001279105,0.0001211343,0.00037343,0.000001509227,0.000007377248,0.000009685411,0.00003153437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2501235,"threshold_uncertainty_score":0.3063858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009550007511920618,"score_gpt":0.2338899583379543,"score_spread":0.2243399508260337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}