{"id":"W2015833555","doi":"10.1208/aapsj070357","title":"Mucosal delivery of bacterial antigens and CpG oligonucleotides formulated in biphasic lipid vesicles in pigs","year":2005,"lang":"en","type":"article","venue":"The AAPS Journal","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Oligonucleotide; Lipid vesicle; Vesicle; Antigen; CpG Oligodeoxynucleotide; Chemistry; Biology; Molecular biology; Microbiology; Immunology; DNA; Biochemistry; Gene; DNA methylation; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007718024,0.0006292603,0.0008312232,0.0006076133,0.0003179359,0.0007309713,0.0006176882,0.001441531,0.00100824],"category_scores_gemma":[0.0003886551,0.000503601,0.0006613166,0.0002186169,0.0007553005,0.001009458,0.0003855082,0.001468455,0.0005644024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006130715,"about_ca_system_score_gemma":0.0005151476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001154871,"about_ca_topic_score_gemma":0.0008860678,"domain_scores_codex":[0.9994246,0.0001269716,0.00002485046,0.0001565624,0.00006428004,0.0002026655],"domain_scores_gemma":[0.9997551,0.00006692427,0.0000732176,0.00002606773,0.00002186071,0.00005693032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004063209,0.0009895897,0.0003928798,0.000201355,0.00002646773,0.0003035824,0.0001242524,0.0002730511,0.9862998,0.0002800095,0.0001181359,0.006927678],"study_design_scores_gemma":[0.0006475099,0.05078042,0.004377808,0.00006985068,0.0002039918,0.0004338213,0.0002621291,0.001654577,0.9383245,0.0002276674,0.002984484,0.00003323432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943136,0.001099769,0.002337093,0.000194673,0.0001348259,0.0001406192,0.0001748434,0.00008280432,0.001521818],"genre_scores_gemma":[0.9917915,0.001095203,0.002104808,0.0001418969,0.00003258588,0.0001196304,0.0002238866,0.00002850481,0.004462059],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001441531,"threshold_uncertainty_score":0.004448235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009550007511920618,"score_gpt":0.2338899583379543,"score_spread":0.2243399508260337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}