{"id":"W2015890305","doi":"10.1007/s00381-011-1595-6","title":"Genetic–environmental interaction in a unique case of Muenke syndrome with intracranial hypertension","year":2011,"lang":"en","type":"article","venue":"Child s Nervous System","topic":"Craniofacial Disorders and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Human Genome Research Institute; NHLBI Division of Intramural Research; National Institutes of Health","keywords":"Craniosynostosis; Medicine; Vitamin; Pediatrics; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003467022,0.0001353437,0.0001714207,0.00004577843,0.00004604641,0.000004590646,0.00005984445,0.00009575119,0.00001197939],"category_scores_gemma":[0.000002256816,0.0001117744,0.00004973028,0.00004399257,0.00004134229,0.000004231878,0.00003384204,0.00005724634,0.000005780528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002776849,"about_ca_system_score_gemma":0.00001270531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009240704,"about_ca_topic_score_gemma":0.0006234965,"domain_scores_codex":[0.9993185,0.00004481552,0.0002007661,0.0002405721,0.00005882197,0.0001365209],"domain_scores_gemma":[0.9996436,0.000002275285,0.00008278192,0.0002137409,0.00001116264,0.00004641512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005316742,0.00650923,0.6053964,0.0009523258,0.001313077,0.09119384,0.00503466,0.0005535012,0.2415882,0.0004001749,0.0001401087,0.04160162],"study_design_scores_gemma":[0.006687466,0.003876939,0.7902465,0.0005390923,0.000205955,0.1607254,0.006954819,0.0006135588,0.0289494,0.00001780718,0.0003331433,0.0008499925],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998245,0.0001684268,0.0001655945,0.00000480102,0.00008203029,0.0002828098,0.00002211903,0.00000896143,0.001020254],"genre_scores_gemma":[0.9995935,0.00002810456,0.0002511472,0.00001798742,0.00002367389,0.0000194313,0.00002688513,0.00002094609,0.00001833356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2126388,"threshold_uncertainty_score":0.455803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007270411446294978,"score_gpt":0.1846475710439323,"score_spread":0.1773771595976373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}