{"id":"W2015890999","doi":"10.1242/dev.00851","title":"Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction","year":2003,"lang":"en","type":"article","venue":"Development","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":151,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"GLI3; GLI2; Biology; GLI1; Sonic hedgehog; Somite; Hedgehog signaling pathway; Cell biology; Transcription factor; Repressor; Genetics; Signal transduction; Embryo; Gene; Embryogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000162335,0.0003339034,0.000201384,0.0001708202,0.000174568,0.000404302,0.0001814287,0.0002059713,0.0006764657],"category_scores_gemma":[0.0001486548,0.000256591,0.000198753,0.0001201447,0.0002651949,0.0002695262,0.000314966,0.0003029986,0.0003838875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003737024,"about_ca_system_score_gemma":0.0003830898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007659905,"about_ca_topic_score_gemma":0.001431405,"domain_scores_codex":[0.9998689,0.00001839149,0.000009995908,0.00001809162,0.00003853815,0.00004615471],"domain_scores_gemma":[0.9998926,0.00001740063,0.0000220215,0.00001053377,0.0000121934,0.00004526169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001320258,0.000006628347,0.0003430804,0.00001508453,0.000002359044,0.00004605972,0.000006237531,0.00005187496,0.9986736,0.0001331102,0.00001440057,0.0005756455],"study_design_scores_gemma":[0.00002318639,0.00009083686,0.01330775,0.000003126831,0.00001611533,0.0004875945,0.00003704822,0.001217125,0.9835118,0.0001984173,0.00110112,0.000005851128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950759,0.001018535,0.001686079,0.00005630656,0.000008386648,0.000009114027,0.0001335577,0.00004885644,0.001963192],"genre_scores_gemma":[0.9966699,0.0005235495,0.001297374,0.00003249102,0.000006633034,0.00001736428,0.0002018538,0.00002628876,0.001224646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007659905,"threshold_uncertainty_score":0.002711415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02126506585906207,"score_gpt":0.2412880834576009,"score_spread":0.2200230175985388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}