{"id":"W2015913136","doi":"10.1016/j.aca.2009.12.001","title":"A mixed film composed of oligonucleotides and poly(2-hydroxyethyl methacrylate) brushes to enhance selectivity for detection of single nucleotide polymorphisms","year":2009,"lang":"en","type":"article","venue":"Analytica Chimica Acta","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Oligonucleotide; Selectivity; Chemistry; Methacrylate; 2-Hydroxyethyl Methacrylate; Nucleotide; Ionic strength; Polymer chemistry; Analytical Chemistry (journal); Chromatography; Polymer; Copolymer; DNA; Organic chemistry; Aqueous solution; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003768753,0.000373563,0.0002597898,0.0002099736,0.0001948824,0.0002368084,0.0002918869,0.0006251792,0.001117787],"category_scores_gemma":[0.0002918452,0.0003468058,0.0001975586,0.0001697803,0.0001432614,0.0002906309,0.0002028411,0.000556885,0.0003048879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001876981,"about_ca_system_score_gemma":0.0002062395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004172714,"about_ca_topic_score_gemma":0.001697661,"domain_scores_codex":[0.9998206,0.000024226,0.00001434344,0.0000577592,0.00005406759,0.0000289836],"domain_scores_gemma":[0.9998678,0.00003701307,0.00001703849,0.00001079035,0.00003310412,0.00003415121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001186663,0.000004947869,0.00002304347,0.00001636213,0.000002270997,0.00001330908,0.000003600974,0.00000564975,0.9994197,0.00001668157,0.00001376496,0.0004688706],"study_design_scores_gemma":[0.000008270416,0.0001033655,0.0004985777,0.000003673519,0.00001696111,0.0001193321,0.000005810082,0.0006138818,0.9973942,0.00001163391,0.001221256,0.000002832694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9626588,0.00354533,0.03046386,0.0003170873,0.0002150006,0.0001177418,0.0001313664,0.000328513,0.00222218],"genre_scores_gemma":[0.9355916,0.001579329,0.05462147,0.0003921842,0.0000644085,0.0001057552,0.0002322817,0.00004458928,0.007368466],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001117787,"threshold_uncertainty_score":0.003739417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01082173260522329,"score_gpt":0.265656178588757,"score_spread":0.2548344459835337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}