{"id":"W2015931889","doi":"10.1158/0008-5472.sabcs-09-4068","title":"A Quantitative Immunofluorescence Assay (AQUA) Suggests Significant Misclassification (15%) of Estrogen Receptor Status in Breast Cancer.","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Biosensing Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Estrogen receptor; Breast cancer; Estrogen; Cancer; Biology; Medicine; Oncology; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008174604,0.0005393719,0.0004189516,0.001821672,0.0005779586,0.0007888271,0.0009376424,0.001032903,0.001894183],"category_scores_gemma":[0.005836786,0.000429831,0.0004739571,0.001088341,0.00113952,0.0005227779,0.0006097276,0.0007381176,0.0005625772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009425706,"about_ca_system_score_gemma":0.0003295829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001525093,"about_ca_topic_score_gemma":0.002428242,"domain_scores_codex":[0.9947606,0.00176558,0.0005205081,0.001257724,0.001467791,0.0002278291],"domain_scores_gemma":[0.9945385,0.002279783,0.00146837,0.000822517,0.0007819412,0.0001089536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006434887,0.0002348583,0.4564276,0.0006514591,0.0004288076,0.000576988,0.0005623962,0.0007806427,0.4877587,0.002249501,0.003531366,0.04615418],"study_design_scores_gemma":[0.00002672638,0.0007112983,0.6043915,0.0001708052,0.0002557638,0.004832121,0.0003722828,0.006413362,0.3719111,0.001587017,0.009272736,0.00005537264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8820392,0.004981829,0.09788431,0.0007807903,0.0002842043,0.0002709983,0.001820428,0.0009334862,0.01100486],"genre_scores_gemma":[0.9519929,0.0006781664,0.04172541,0.0004324389,0.00003483924,0.0002695537,0.001510809,0.00006238773,0.003293543],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008174604,"threshold_uncertainty_score":0.0432319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04903312932946203,"score_gpt":0.4122431608567914,"score_spread":0.3632100315273294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}